| Objective To determine the difference of hip bone mineral density between femoral neck fracture and intertrochanteric fracture in women with osteoporosis, and to explore the correlation between hip fracture (femoral neck fracture, intertrochanteric fracture) and bone mineral density at the fracture site in patients with osteoporosis. Methods A retrospective analysis of 172 patients with osteoporosis and hip osteoporotic fractures who were hospitalized in a tertiary A hospital in Fujian Province from January 1, 2015 to December 31, 2016, including 109 cases of patients with a history of primary osteoporosis, 39 patients with osteoporotic femoral neck fracture, 24 cases of osteoporotic fracture between the rotor. The age, body mass index, prevalence of diabetes, fracture side, bone density of each hip area, C-terminal crosslinking telopeptide of type I collagen，procollagen type I N propeptide, 25-OH-VitD were calculated respectively. Comparisons were made among three groups and two groups. Results There were no significant differences in age, body mass index, and diabetes prevalence among the three groups (F=2.667, P=0.072; F=0.882, P=0.416; χ2=3.216, P=0.232). There was no statistically significant difference in hip ward area density difference between the femoral neck fracture group and the femoral intertrochanteric fracture group(χ2=0.958, P =0.328), and there was no statistically significant difference in the bone mineral density of the hip ward area among the three groups (F=2.937, P=0.056).The comparison of hip bone mineral density, femoral neck, femoral greater trochanter, between the femur rotor, hip overall were statistically significant (F=7.825，P<0.05,P=0.001; F=8.668, P<0.001; F=9.657，P<0.001).The overall BMD of femoral neck, greater trochanter, intertrochanteric and hip in the femoral neck fracture group and the intertrochanteric fracture group were all lower than those in the osteoporosis group, and the difference was statistically significant (P<0.05).The overall BMD of femoral neck, greater trochanter, intertrochanter and hip in the femoral neck fracture group and the intertrochanteric fracture group were not statistically significant (P>0.05). There were significant differences in β-CTX, P1NP and vitamin DT among the three groups (P<0.05). The β-CTX and vitamin DT of the femoral neck fracture group and the intertrochanteric fracture group were less than those of the osteoporosis group, and the difference was statistically significant (P<0.05).There was no statistically significant difference in P1NP between the intertrochanteric fracture group and the osteoporosis group, and there was no statistically significant difference in bone mineral density between the femoral neck fracture group and the intertrochanteric fracture group in the femoral neck, greater trochanter, intertrochanter, and hip (P>0.05). Conclusion: The type of hip fracture in female patients with osteoporosis may not depend on the local bone density, but may be related to bone microstructure and other factors. It may be a clear and reliable study that needs further research to confirm. |