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| 扶元乳膏穴位贴敷治疗骨质疏松性椎体压缩骨折患者PKP术后残留腰背痛的疗效观察 |
| Effects of acupoint application therapy with Fuyuan Rugao in the treatment of residual low back pain in patients with OVCF after PKP |
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| DOI：10.3969/j.issn.1006-7108.2020.10.021 |
| 中文关键词: 骨质疏松性椎体压缩骨折 扶元乳膏 穴位贴敷 残留腰背痛 中医中药 |
| 英文关键词:osteoporosis vertebral compression fracture Fuyuan Rugao acupoint application residual low back pain Chinese medicine |
| 基金项目:广东省中医药局科研课题面上项目（20201298）；深圳市科技创新委员会基础研究项目（JCYJ20180302144355408 ）；深圳市宝安区科技创新局基础研究项目（2018JD023 ） |
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| 中文摘要: |
| 目的 探讨扶元乳膏穴位贴敷治疗骨质疏松性椎体压缩骨折（OVCF）经皮推体后凸成形术（PKP）术后残留腰背痛的临床疗效。方法 将2018年3月至2019年12月深圳市中西医结合医院住院部的70例患者，按就诊顺序随机分为观察组、对照组。对照组给予中药热奄包外敷，观察组行扶元乳膏穴位贴敷，两组患者均口服抗骨质疏松药物。记录比较两组患者治疗前和治疗后的视觉模拟疼痛评分（VAS评分）、Oswestry残损指数（ODI评分）、血清Ⅰ型胶原氨基端延长肽（P1NP）、骨碱性磷酸酶（BALP）、I型胶原交联C-末端肽（β-CTX）含量变化及临床疗效。结果 治疗后，2 组患者较治疗前的VAS 评分、ODI 评分及血清β-CTX含量均明显降低，而血清P1NP、BALP含量则显著升高( P 均＜0.05) ；与对照组比较，观察组治疗后的VAS 评分、ODI 评分及血清β-CTX含量显著降低，而血清P1NP、BALP含量则明显升高，差异比较均有统计学意义（P 均＜0.05）；观察组、对照组治疗总有效率分别为97.1%、85.7%，两组临床疗效差异比较具有统计学意义（P＜0.05）。结论 扶元乳膏穴位贴敷可有效缓解骨质疏松性椎体压缩骨折PKP术后残留腰背痛，改善临床症状和骨代谢，值得临床推广应用。 |
| 英文摘要: |
| Objective To observe the effect of Acupoint Application Therapy with Fuyuan Rugao in the Treatment of Residual low back pain in Patients with osteoporosis vertebral compression fracture(OVCF) after percutaneous kyphoplasty(PKP).Methods From March 2018 to December 2019, 70 patients in the inpatient department of Shenzhen Hospital of Integrated Chinese and Western Medicine were randomly divided into observation group and control group according to treatment time. Both groups were treated with oral anti osteoporosis drugs. The observation group was treated by acupoint Application of with Fuyuan Rugao，and the control group were treated with external application of Chinese medicine hot package. The changes of VAS score, ODI index，type Ⅰ procollagen amino-terminal peptide（P1NP）,bone specific alkaline phosphatase（BALP）, β collagen specific sequence（β-CTX）and clinical effect were compared before and after treatment. Results After treatment, the VAS score, ODI index,and serum β-CTX content of the two groups were significantly reduced , while the serum P1NP and BALP levels of the two groups were significantly increased. Compared with the control group, the VAS score, ODI score and β-CTX content of the observation group were significantly reduced, while the serum P1NP and BALP content levels were significantly increased (P < 0.05).The total effective rate of the observation group and the control group were 97.1% and 85.7%, respectively. The clinical efficacy of the two groups was statistically significant (P <0.05).Conclusion Acupoint Application Therapy has a significant clinical effect in the treatment of residual low back pain in patients with OVCF after PKP. It can quickly improve the clinical symptoms and regulate bone metabolism of patients. This therapy deserve clinical expansion. |
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