| Objective To investigate the effect of bone cemented and biological prostheses hemiarthroplasty on postoperative trauma and bone metabolism in the elderly patients with femoral neck fracture. Methods 60 elderly patients with femoral neck fracture who have underwent hemiarthroplasty in our hospital from January 2018 to January 2020 were selected and divided into cemented type group and biological type group with 30 cases each according to prosthesis type. The levels of inflammatory factors [tumor necrosis factor-α(TNF-α), interleukin-6(IL-6), procalcitonin (PCT), C- reactive protein (CRP)], stress hormones [norepinephrine (NE), epinephrine (E), cortisol (Cor)], bone metabolic markers [type I collagen carboxy-terminal peptide β special sequence (β-CTX), total type I collagen amino-terminal elongation peptide (tPINP), bone alkaline phosphatase (BALP), whole-segment parathyroid hormone (iPTH)] were compared between the two groups on preoperative and the 1st and 7th day after operation . Results The levels of inflammatory factors (TNF-α, IL-6, PCT, CRP) and bone metabolism (β-CTX, tPINP, BALP, iPTH) were not statistical significance between the two groups (P >0.05) on preoperative and the 1st and 7th day after operation. The levels of stress hormone (NE, E, COR) between the two groups were not statistical significance on preoperative and the 7th day after operation (P> 0.05), but on the 1st day after operation (P < 0.05). Conclusion There is no difference in inflammatory factors and bone metabolism between the two prosthesis surgeries for elderly patients with femoral neck fracture. However, biological prostheses have little effect on stress hormone and have more advantages for patients with many basic diseases and poor surgical tolerance. |