中国骨质疏松杂志

免疫系统在绝经后骨质疏松症中的作用

The role of the immune system in postmenopausal osteoporosis

DOI：10.3969/j.issn.1006-7108.2020.10.027

英文关键词:Postmenopausal osteoporosis Immune cells Cytokines Estrogen

基金项目:

作者	单位
张晓红1* 高艳丽1 袁征2 刘钇彤3	1.郑州卫生健康职业学院基础医学系，河南郑州 450000 2.郑州卫生健康职业学院基护教学部，河南郑州 450000 3.郑州市人民医院健康管理中心，河南郑州 450000

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中文摘要:

随着我国老龄人口的不断增加，绝经后骨质疏松症（postmenopausal osteoporosis，PMOP）的发病率在不断增加。雌激素的减少导致的骨量丢失是引起PMOP的主要原因。雌激素引起骨量丢失的机制十分复杂，而且与免疫系统密切联系。本文将对免疫系统在PMOP的作用进行简要综述，以期为本病的治疗提供一种新的思路。

英文摘要:

With the continuous increasing number of elderly people in China, the incidence of postmenopausal osteoporosis (PMOP) is also increasing. The loss of bone mass caused by the reduction of estrogen is the main cause of PMOP. The mechanism of estrogen causing bone loss is very complicated and closely linked with the immune system. This article will briefly review the role of the immune system in PMOP, in order to provide a new idea for the treatment of this disease.

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