中国骨质疏松杂志

中国老年男性骨质疏松症影响因素的Meta分析

Meta-analysis of the influencing factors of osteoporosis in Chinese elderly men

DOI：10.3969/j.issn.1006-7108.2021.02.007

英文关键词:elderly men osteoporosis influencing factors Meta-analysis

基金项目:吉林省教育厅“十三五”科学技术项目(JJKH20191159KJ)

作者	单位
夏晓妹1 杨士鹏2 葛若兰1 崔立敏2*	1 延边大学护理学院，吉林延吉 133000 2 延边大学附属医院骨一科，吉林延吉 133000

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中文摘要:

目的通过Meta分析明确中国老年男性罹患骨质疏松（osteoporosis, OP)的主要影响因素。方法使用计算机检索中国知网、万方数据库、维普网、PubMed、Web of Science、Embase数据库(自建库以来至2020年1月)，并使用NOS进行文献质量评价，使用RevMan 5.3进行Meta分析。结果共纳入21篇研究，提取18个相关的影响因素。Meta分析结果显示，年龄、身高、体重、体质量指数（body mass index,BMI)、骨密度（bone mineral density, BMD)、文化水平、骨折史、血清钙水平、吸烟、日光照射、运动锻炼、饮茶、补钙史、饮牛奶、补维生素D史与我国老年男性罹患OP相关，比较差异有统计学意义(Р<0.05)；与饮酒、25-(OH)D水平、血清磷水平方面比较差异无统计学意义(Р>0.05)。结论体重、BMI、BMD、饮牛奶、补钙、补维生素D、血清钙水平、饮茶、运动锻炼、日光照射及文化水平是我国老年男性罹患OP的保护因素；年龄、身高降低、吸烟、骨折史是危险因素；饮酒、25-(OH)D水平、血清磷水平需进一步验证。

英文摘要:

Objective To identify the main influencing factors of OP in the elderly men in China through Meta-analysis. Methods The literatures of CNKI, Wanfang Database,VIP Network, PubMed,Web of Science,Embase Database(from inception to January 2020)were screened. The quality was evaluated according to NOS.Meta-analysis was performed using a RevMan5.3 software. Results A total of 21 reference were included,18 influencing factors were extracted. Meta-analysis showed that age, height, weight,BMI, BMD, education level, fracture history, serum calcium level, smoking,sunlight exposure, exercise, drinking tea, calcium supplement history,drinking milk and vitamin D supplementation history were associated with OP, and the differences were statistically significant(P＜0.05).There were no statistically significant(P＞0.05) in drinking, 25-(OH)D and serum phosphorus level. Conclusion Body weight, BMI, BMD, milk drinking, calcium supplement, vitamin D supplement, serum calcium level, tea drinking,exercise, sunlight exposure and cultural level were protective factors; age, loss of height, smoking and fracture history were the risk factors; The factors of drinking, 25-(OH)D and serum phosphorus level need to be further vertified.

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