老年女性冠心病人群骨质疏松的患病率及相关因素分析
Analysis of the prevalence of osteoporosis and associated factors in older women with coronary heart disease population
  
DOI:10.3969/j.issn.1006-7108.2021.02.019
中文关键词:  老年女性  骨质疏松  冠心病  影响因素
英文关键词:elderly women  osteoporosis  coronary heart disease  influencing factor
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作者单位
高开茜* 雷建华 徐春鹏 剧晓静 耿芸 石家庄市第五医院综合内科河北 石家庄 050000 
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中文摘要:
      目的 调查老年女性冠心病人群骨质疏松的患病率及相关影响因素,为两种疾病的协同防治提供更多的理论依据。 方法 成功搜集并调查了181例诊断为冠心病并行骨密度检测的老年女性患者,包括年龄、家庭、身高、体重、收入、居住地等基本情况,根据是否存在骨质疏松分为观察组(骨质疏松人群)及对照组(骨量正常人群)。通过单因素及多因素 Logistic 回归分析老年女性冠心病人群合并骨质疏松的患病率及影响因素,并联合ROC曲线对模型进行了预测。结果 冠心病合并骨质疏松者110例,患病率为60.8%,其中农村高收入人群及城市低收入人群发病率较高(P<0.05);单因素分析显示,年龄、体质量指数(body mass index, BMI)、高血压、糖尿病、冠心病家族史、吸烟史及婚姻状态在两组患者中分布不同 ( P<0.1) ; 多因素Logistic回归分析显示,高龄、高血压、糖尿病、冠心病家族史、吸烟史及BMI≥28 kg/m2是冠心病人群发生骨质疏松的危险因素(P<0.05);ROC曲线结果为AUC=0.820,P<0.001。结论 ①高龄、高血压、糖尿病、冠心病家族史、吸烟史及BMI≥28 kg/m2是老年女性冠心病人群发生骨质疏松的独立危险因素,同冠心病危险因素基本保持一致,两病协同防治存在共同的病因基础;②影响因素中,社会因素不可忽视,而改变生活方式、增加对疾病的了解可能会降低其发生率。
英文摘要:
      Objective To investigate the prevalence of osteoporosis and related influencing factors in the elderly females with coronary heart disease, so as to provide more theoretical basis for the coordinated prevention and treatment of the two diseases. Methods 181 elderly female patients with a diagnosis of coronary heart disease were successfully collected, and performed bone density testing, and investigated the basic situation, including basic information such as age, family, height, weight, income, and place of residence, and so on. According to the presence or absence of osteoporosis, they were divided into an observation group and a control group. The prevalence and influencing factors of osteoporosis in elderly women with coronary heart disease were analyzed by a single factor and multi-factor Logistic regression, and the model was predicted by combining with the ROC curve. Results There are 110 patients with coronary heart disease and osteoporosis, the prevalence rate is 60.8%, and the incidence is higher in rural high-income people and urban low-income people (P<0.05); Univariate analysis showed that age, BMI, hypertension, diabetes, coronary heart disease family history, smoking history, and marital status were distributed differently in the two groups (P<0.1); Multivariate logistic regression analysis showed that advanced age, hypertension, diabetes, family history of coronary heart disease, smoking history and BMI≥28 kg/m2 were the risk factors for osteoporosis in coronary heart patients (P<0.05); The results of ROC curve: AUC=0.820, P<0.001.Conclusion ①Old age, hypertension, diabetes, family history of coronary heart disease, smoking history, and BMI≥28 kg/m2 are the independent risk factors for osteoporosis in the elderly female coronary heart patients. These risk factors are consistent with coronary heart disease risk factors. Therefore, there is a common etiological basis for the cooperative prevention and treatment of the two diseases; ②Among these influencing factors, social factors cannot be ignored, and changing lifestyles and increasing understanding of the disease may reduce its incidence.
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