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| 骨关节炎与骨质疏松症的相关性研究分析 |
| Analysis of the correlation between osteoarthritis and osteoporosis |
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| DOI：10.3969/j.issn.1006-7108.2021.02.024 |
| 中文关键词: 骨质疏松 骨关节炎 骨密度 物理治疗 |
| 英文关键词:osteoporosis osteoarthritis bone mineral density physical therapy |
| 基金项目:国家自然科学基金青年科学基金项目（81802234）；重庆市卫计委重点项目（2016ZDXM009）；重庆市体育局项目（B201805）；重庆市科委集成示范项目（csct2015jcsf10006） |
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| 中文摘要: |
| 骨质疏松症（osteoporosis, OP）及骨关节炎（osteoarthritis，OA）是两种常见的老年性疾病，随着我国人口老龄化程度的不断加剧，它们已成为影响老年人生活质量的两大主要骨与关节疾患。为了进一步阐述两者的相互关系，笔者以国内外骨关节炎和骨质疏松症相关性的最新研究为基础，总结了两者之间的可能联系。笔者发现，骨质疏松症与骨关节炎之间存在以下的可能关系：①正相关性：较高的骨密度水平不仅对于OP的发生有延缓和阻碍作用，对于延缓 OA的发展也有积极作用；骨质疏松症可能是骨关节炎的病因之一，发病机制上也有共同点；②负相关性：高骨密度可以降低OP患者的骨折风险，但患OA的风险增加；③无相关性。同时，在治疗上，已有许多研究尝试将治疗骨质疏松的药物（双膦酸盐、降钙素、维生素D3、雌激素等）用于治疗骨关节炎；物理治疗方面，运动疗法、超声、振动疗法等均表现出对于这两种疾病的双重治疗作用。 |
| 英文摘要: |
| Osteoporosis (OP) and osteoarthritis (OA) are two common senile diseases. As China's population ages, they have become two major bone and joint diseases affecting the quality of life of the elderly. To further illustrate the interrelationship between osteoarthritis and osteoporosis, we summarized the possible connections based on the latest domestic and international researches on the correlation between osteoarthritis and osteoporosis. We found that the possible relationships between osteoporosis and osteoarthritis: ①Positive correlation: A higher bone mineral density not only delayed and hindered the occurrence of OP, but also played a positive role in delaying the development of OA; Osteoporosis might be one of the causes of osteoarthritis; There were also similarities in pathogenesis. ②Negative correlation: High bone mineral density could reduce the risk of fracture in OP patients, but increased the risk of OA.③No correlation. In terms of treatment, there have been many studies trying to apply osteoporosis drugs (bisphosphonates, calcitonin, vitamin D3, estrogen, etc.)to treat osteoarthritis . Physical therapy, exercise therapy, ultrasound, vibration and other therapies may work for both OP and OA. |
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