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| 骨质疏松症骨髓脂肪的影像学研究进展 |
| Progress on imaging research of bone marrow fat in osteoporosis |
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| DOI：10.3969/j.issn.1006-7108.2021.02.025 |
| 中文关键词: 骨质疏松症 骨髓 脂肪 体层摄影术，X线计算机 磁共振成像 |
| 英文关键词:osteoporosis bone marrow fat tomography, X-ray computed magnetic resonance imaging |
| 基金项目:上海市科学技术委员会医学引导类（西医）科技支撑项目（19411965300）；国家自然科学基金面上项目（81871325）；上海市卫生和计划生育委员会面上项目（201640092）；中央高校基本科研业务费专项资金资助项目（22120180380） |
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| 中文摘要: |
| 骨质疏松症（osteoporosis，OP）是一种以骨强度降低、易导致脆性骨折为特征的全身代谢性疾病。骨髓脂肪细胞是影响OP发生、发展的重要因素。早期监测骨髓脂肪含量的变化有助于OP的临床诊断和治疗。已有较多影像学方法用于OP骨髓脂肪的评估，包括双能定量CT、显微CT、水脂分离技术以及磁共振波谱，本文就这些影像学方法对OP骨髓脂肪的研究进展进行综述。 |
| 英文摘要: |
| Osteoporosis (OP) is a systemic metabolic disease characterized by decreased bone strength and fragility fracture. Bone marrow adipocytes are the important factors that affect both the occurrence and development of OP. Early detection of changes in bone marrow fat content will be helpful for the clinical diagnosis and the treatment of OP. Many imaging methods, including dual energy quantitative CT, Micro-CT, water-fat separation technique, and magnetic resonance spectrum, have been used to evaluate bone marrow fat in OP. The present paper summarizes the research progress of OP bone marrow fat with these imaging methods. |
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