中国骨质疏松杂志

基于肾之“精气”“阴阳”理论探析绝经后骨质疏松症的病机变化

Analysis of the pathogenesis of postmenopausal osteoporosis based on the theory of essence and Qi, and Yin and Yang of the kidney

DOI：10.3969/j.issn.1006-7108.2021.03.021

中文关键词: 中医中药肾虚阴阳失衡绝经后骨质疏松症病机变化

英文关键词:Chinese traditional medicine deficiency of the kidney imbalance of Yin and Yang postmenopausal osteoporosis pathogenesis

基金项目:国家自然科学基金（81774185）

作者	单位
冯秀芝1 吴继雷2 任艳玲1*	1.辽宁中医药大学中医学院，辽宁沈阳 110847 2.辽宁中医药大学附属医院，辽宁沈阳 110032

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中文摘要:

中医学防治绝经后骨质疏松症具有完善的理论体系、确切的临床疗效，中医药的现代研究又为其防治绝经后骨质疏松症提供了客观依据。基于古代文献和中医临床立法用药规律，结合现代医学对绝经后骨质疏松症发病机制的研究，围绕肾之“精气”“阴阳”理论阐释绝经后骨质疏松症的病机变化为以肾精亏虚为先导，继而肾之阴阳平衡失调，导致骨髓失养、代谢紊乱、骨枯形伤，出现疼痛、骨量减少、骨强度下降、骨脆性增加、易于骨折等临床表现。

英文摘要:

The prevention and treatment of postmenopausal osteoporosis with traditional Chinese medicine has a perfect theoretical system and definite clinical efficacy. Modern research in traditional Chinese medicine has provided an objective basis for the prevention and treatment of postmenopausal osteoporosis. Based on ancient literature and the laws of traditional Chinese medicine clinical legislation, combined with the research of modern medicine on the pathogenesis of postmenopausal osteoporosis, the pathogenesis of postmenopausal osteoporosis is explained based on the essence and Qi, and Yin and Yang theory of the kidney. Deficiency of essence is a guide, followed by imbalance of Yin and Yang in the kidney, leading to bone marrow dystrophy, metabolic disorders, bone withering and shape injury, pain, decreased bone mass, decreased bone strength, increased bone fragility, and vulnerable to fractures.

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