绝经女性骨质疏松和代谢综合征各组分之间的相关性研究
Study on the correlation between osteoporosis and metabolic syndrome in menopausal women
  
DOI:10.3969/j.issn.1006-7108.2021.04.018
中文关键词:  PMOP  代谢综合征  高血压  糖尿病
英文关键词:PMOP  metabolic syndrome  hypertension  diabetes
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作者单位
包少瑜1 孙兢1 张智海2* 1. 中国人民大学医院北京 100872 2. 航空总医院北京 100012 
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中文摘要:
      目的 探讨绝经后骨质疏松(postmenopausal osteoporosis,PMOP)和代谢综合征各组分之间的相关性。方法 选取2017年1月至2019年12月在我院收治的PMOP患者59例,作为研究组;选取同期来我院行健康体格检查的人群256例,作为对照组。结果 研究组BMI、Ca水平、GFR低于对照组(P<0.05),研究组年龄、HDL-C水平高于对照组(P<0.05),研究组骨折率、高血压率高于对照组(P<0.05),其他一般资料水平差异无统计学意义(P>0.05)。研究结果提示,不同年龄段年龄、不同BMI水平、是否合并高血压、不同HDL-C水平及不同CHOL水平下的PMOP检出率差异存在统计学意义(P<0.05)。骨质疏松的发生与HDL-C水平、CHOL水平、BMI水平、年龄之间存在相关性;HDL-C水平跟PMOP的发生之间呈正相关性,年龄是PMOP发生的独立风险因素。结论 POMP的发生与代谢综合征之间存在一定的相关性,在临床中应当依据不同个体的实际情况来给予指导干预,从而降低其发生PMOP的风险及比率。
英文摘要:
      Objective To investigate the correlation between postmenopausal osteoporosis (PMOP) and various components of metabolic syndrome. Methods 59 cases of PMOP patients admitted to our hospital from January 2017 to December 2019 were selected as the research group; 256 patients who came to our hospital for sexual health examination during the same period were selected as the control group. Results The BMI, Ca level and GFR of the study group were lower than that of the control group (P<0.05), the age and HDL-C level of the study group were higher than the control group (P<0.05), and the fracture rate and hypertension rate of the study group were higher than the control group (P<0.05), there was no significant difference in the level of other general data (P>0.05). The results of the study suggest that there was a significant difference in the detection rate of PMOP at different ages, different BMI levels, whether there was hypertension, different HDL-C levels, and different CHOL levels (P<0.05). There was a correlation between the occurrence of osteoporosis and HDL-C level, CHOL level, BMI level, and age; HDL-C level was positively correlated with the occurrence of PMOP, and age was an independent risk factor for the occurrence of PMOP. Conclusion There is a certain correlation between the occurrence of POMP and metabolic syndrome. In clinical practice, guidance intervention should be given according to the actual situation of different individuals, so as to reduce the risk and rate of PMOP.
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