| Objective To evaluate the correlation between serum 25(OH)D level and bone mineral density in Chinese adults. Methods Retrieval the databases of Wanfang, CNKI, VIP, time from the establishment until January 30, 2020. The quality of the literatures were assessed by the Agency for Healthcare Research and Quality standard. Meta-analysis was conducted via the software R 3. 6. 3. Results A total of 24 literatures were included, the total sample size was 6 305, and the literature quality evaluation grade was relatively high. Meta analysis results: Serum 25(OH)D level was significantly correlated with bone mineral density Fisher's Z value of lumbar spine 1-4 vertebrae, total hip and femoral neck, which were [Fisher’Z=0.16, 95% CI(0.15, 0.19), P<0.05], [Fisher’Z=0.12, 95% CI (0.09, 0.15), P<0.05], [Fisher’Z=0.15, 95% CI(0.11, 0.12), P<0.05], summary r was 0. 16, 0.12 and 0.15, respectively. There was no distinct publication bias, and the sensitive analysis results were stable. Conclusion There is a significant positive correlation between serum 25(OH)D level and bone mineral density in adults in China, and the degree is extremely weak. Taking the low level of evidence into consideration, further strict academic proof is needed. |