| Objective To investigate the effect of parathyroidectomy on muscle function in patients with secondary hyperparathyroidism. Methods Twenty-nine patients with secondary hyperparathyroidism who underwent parathyroidectomy at our hospital from August 1, 2018 to July 31, 2019 were collected, and general clinical data and biochemical parameters were collected preoperatively, and upper arm circumference, triceps skinfold thickness, grip strength, and 6-meter average gait speed were measured preoperatively, 6 months postoperatively, and 12 months postoperatively to investigate the effect of parathyroidectomy on the Effect of muscle function in patients with secondary hyperparathyroidism. Results ①The iPTH level of the patient was significantly reduced after the operation, from 1 395.7pg/mL(974,1858.3) before the operation to 39.6 pg/mL (27.3, 65.4)(P=0.00), and the patient's clinical symptoms were alleviated.②The changes of upper arm circumference, triceps brachii skin fold thickness and upper arm muscle circumference were not statistically significant compared with those before surgery (P>0.05);The BMI adjusted upper brachial muscle circumference was significantly increased in both female patients 6 months and 12 months after surgery (P<0.05), and in male patients 6 months and 12 months after surgery (P<0.05, P<0.01). ③ The grip strength increased in male patients at 6 and 12 months after surgery, with significant differences compared with preoperative (P<0.05), and in female patients at 12 The difference between grip strength at 12 months and preoperative grip strength was statistically significant (P<0.05), the walking speed of patients of different genders increased in the 6-meter walking test after surgery, and the walking speed increased significantly at 12 months after surgery compared with that before surgery, with statistical significance (P<0.05). Conclusion Parathyroidectomy can improve muscle function in patients with secondary hyperparathyroidism. |