| the basic theory of TCM, known as "the liver advocate muscle, kidney advocate bone", said the liver blood main reinforcement, reinforcement beam of bone and joint, the kidney is the foundation of the nature, the main born bone marrow, liver and kidney JingXie homologous, bones and muscles, mutual information and alternate, the two common mediated the body organs, development, growth and decline of the zang-fu organs, especially closely associated with bone metabolism of cell growth mechanism.With the in-depth study of the molecular biology of traditional Chinese medicine, it has been found that the bone protective protein (OPG)/nuclear factor-kb receptor activating factor (RANK)/nuclear factor-kb receptor activating factor ligand (RANKL) signal axis plays a key role in bone metabolism.In this paper, based on the theory of "liver advocate muscle, kidney advocate bone", starting from the etiology and pathogenesis of postmenopausal osteoporosis, from the perspective of "kidney differentiation, bones and muscles and" OPG/RANKL/RANK signal transduction system combined with bone metabolic homeostasis, traditional Chinese medicine for liver kidney, reinforced bone mechanism provided molecular biology, bones and muscles mechanics on the basis of support, in order to further guide clinical treatment. |