| Diabetic osteoporosis (DOP) is a serious chronic complication caused by sustained high blood glucose in the body skeletal system, which has become one of the main causes of mortality and disability in patients with diabetes mellitus (DM). Bone mineral density (BMD) is one of the commonly used indicators to evaluate bone quality, but it is incompletely suitable for the evaluation of bone quality in individuals with DM, especially with T2DM. This is because a significant increase in fracture risk is observed in patients with T2DM despite normal or even high BMD. Bone quality, mainly including bone mass (BM), bone geometrical structure and material properties, etc., is a comprehensive indicator of bone health. It has been widely applied in the diagnosis of osteoporosis, assessment of the efficacy of anti-DOP drug, prediction of fracture risk, and other aspects of research. In the present study, the detecting approaches that commonly used to evaluate bone quality in the clinic are introduced, which may provide scientific basis for the diagnosis of DOP. |