| Objective To explore the compatibility of traditional Chinese medicine in the treatment of blood stasis type osteoporosis by data mining. Methods The published literatures concerning the treatment of blood stasis type osteoporosis in the database of Chinese journals with full text and other databases were collected and sorted. The screening condition was set, the effective Chinese medicine prescriptions were screened, and the prescription names were standardized. The core medication and prescription rules of blood stasis type osteoporosis were discussed with frequency statistics, cluster analysis, factor analysis and association rule algorithm, and system analysis. Results A total of 127 effective literatures for the treatment of osteoporosis of blood stasis type were selected, involving 160 kinds of traditional Chinese medicine, and the total frequency of drug occurrence was 1459 times. A total of 10 common factors of drug combinations were extracted, and 5 drug combinations were obtained by cluster analysis method of inter group linkage. The core drug combination of association rule analysis was 12 groups. Conclusion Blood stasis type osteoporosis is the syndrome of deficiency and excess, which is related to the liver, spleen and kidney, and is most closely related to kidney. In the treatment, we should take kidney deficiency as the main point, blood stasis as the second, tonifying deficiency as the first and attacking pathogenic factors as the second. At the same time, we should take the liver and spleen into account, pay attention to the application of Qi tonifying and Qi promoting drugs, and regulate Qi and blood simultaneously. |