太极运动防治骨质疏松症的系统评价再评价
Multiple evaluations on Tai Chi for prevention and treatment of osteoporosis: an overview of systematic reviews
  
DOI:10.3969/j.issn.1006-7108.2021.08.006
中文关键词:  太极  骨质疏松症  系统评价再评价  AMSTAR-2  GRADE
英文关键词:Tai Chi  osteoporosis  overview of systematic review  AMSTAR-2  GRADE
基金项目:中医药传承与创新“百千万”人才工程(2100409-重大公共卫生专项 CJJ2018014)
作者单位
刘敏1 周俊2 邱现良2 刘东颖2 陈秋2* 1.成都市龙泉驿区中医医院四川 成都 610100 2.成都中医药大学附属医院四川 成都 610075 
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中文摘要:
      目的 多元评价太极运动防治骨质疏松症相关系统评价的文献质量及其结局指标的证据质量。方法 计算机检索PubMed、Web of science、EMbase、The Cochrane Library、PROSPERO、CNKI、CBM、WanFang和VIP数据库,收集太极运动防治骨质疏松症的系统评价/Meta分析,分别采用AMSTAR-2量表、PRISMA得分对纳入文献进行方法学质量和报告质量评价,并依据GRADE系统对所纳入系统评价的结局指标进行证据质量分级。结果 共纳入13篇系统评价/Meta分析,其中1篇文献方法学质量较高,其余文献均为低或极低质量,PRISMA得分在12~24分不等,主要问题存在于方案注册、偏倚风险评估、异质性、发表偏倚、数据合并分析等方面。GRADE评价结果显示纳入的44个结局指标中,8个结局指标质量为中,22个为低,14个为极低,中等质量的结局指标提示太极运动对脊柱、腰椎、股骨颈的骨密度改善作用优于对照组。结论 太极运动防治骨质疏松症的系统评价/Meta分析文献质量总体不高,结局指标的证据强度较低,未来仍需进行大样本、高质量的研究进一步评估其有效性。
英文摘要:
      Objective To evaluate the quality of literature and the quality of evidence of outcome measures related to systematic reviews of Tai Chi in the prevention and treatment of osteoporosis. Methods PubMed, EMbase, the Cochrane Library, PROSPERO, WBC, CBM, CNKI, WanFang and VIP database were searched to collect systematic reviews of Tai Chi in the prevention and treatment of osteoporosis. The methodological quality and reporting quality of the included studies was evaluated using the AMSTAR-2 scale and PRISMA score respectively, and the outcome measures were graded for the quality of evidence according to the GRADE tool. Results A total of 13 systematic reviews were included, one of the studies had relatively high methodological quality, while the others had low or very low quality. The PRISMA score varied from 12 to 24 points. The main problems existed in protocol registration, risk of bias assessment, heterogeneity, publication bias, data combination and analysis. The GRADE evaluation results showed that of the 44 outcome measures included, 8 outcome measures were of moderate quality, 22 were of low quality, and 14 were of very low quality, and the outcome measures of moderate quality suggested that Tai Chi had a better improvement effect on the spine, lumbar spine, and femoral neck than the control group. Conclusion The systematic reviews of Tai Chi for osteoporosis are generally of low quality and the evidence strength of the conclusions is low, large sample, high-quality studies are still needed to further evaluate its effectiveness in the future.
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