温针灸联合青娥丸对绝经后骨量减少肾虚血瘀证的疗效
Efficacy of warm acupuncture combined with Qing'e pill on postmenopausal bone loss patients with kidney deficiency and blood stasis
  
DOI:10.3969/j.issn.1006-7108.2021.08.019
中文关键词:  温针灸  青蛾丸  骨量减少  肾虚血瘀证
英文关键词:warm acupuncture  Qing'e pill  osteoporosis  kidney deficiency and blood stasis syndrome
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作者单位
管炜1 左封2* 1.武汉市中医医院内分泌科湖北 武汉 430014 2.武汉市第一医院肾病科湖北 武汉 430022 
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中文摘要:
      目的 研究温针灸联合青蛾丸治疗绝经后骨量减少肾虚血瘀证的临床疗效。方法 对2019年6~12月于武汉市中医医院接受治疗的80例绝经后骨量减少肾虚血瘀证患者进行分析。分为两组,每组各40例。对照组予以青蛾丸治疗,试验组在青蛾丸治疗的基础上辅以温针灸疗法,比较两组的临床疗效、骨代谢标志物水平、性激素水平、骨密度及不良反应。结果 试验组(92.50%)总有效率显著高于对照组(72.50%),差异有统计学意义(P<0.05);治疗后两组患者BGP、25-羟维生素D3、β-CTX、PⅠNP、LH、E2、FSH及骨密度均优于同组治疗前,同时试验组优于对照组(P<0.05);对照组与试验组不良反应发生率比较差异无统计学意义(P>0.05)。结论 在青娥丸治疗的基础上辅以温针灸治疗绝经后骨量减少肾虚血瘀证的效果更优,骨量丢失情况得以明显改善,并且不会增加不良反应的发生率。
英文摘要:
      Objective To explore the clinical efficacy of warm needle moxibustion combined with Qing'e pill on postmenopausal bone loss syndrome with kidney deficiency and blood stasis. Methods The study was conducted on 80 postmenopausal patients with osteopenia and kidney deficiency and blood stasis syndrome who were treated in Wuhan Hospital of Traditional Chinese Medicine from June 2019 to December 2019. The patients were randomly divided into two groups, with 40 cases in each group. Patients in the control group received Qing'e pill, while the patients in the observation group received warming acupuncture in addition to Qing'e pill. The efficacy, bone metabolism markers, sex hormone levels, bone mineral density, and adverse reactions were compared between the two groups. Results The total effective rate in the experimental group (92.50%) was significantly higher than that in the control group (72.50%), and the difference was statistically significant (P<0.05). After the treatment, the levels of BGP, 25 hydroxyvitamin D3, β-CTX, PⅠNP, LH, E2, FSH, and bone mineral density were better than those before the treatment in both groups, and those were better in the experimental group than in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the control group and the experimental group (P>0.05). Conclusion On the basis of Qing'e pill treatment, supplement treatment with warm needle moxibustion is better for postmenopausal bone loss syndrome of kidney deficiency and blood stasis. Bone loss can be significantly reversed, and the incidence of adverse reaction does not increase.
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