| Objective To analyze risk factors of osteopenia and osteoporosis in male patients with type 2 diabetes in hospitalized. Methods We included a total of 370 men with type 2 diabetes who had received DXA and aged above 50 years at Tianjin Metabolic Diseases Hospital between January 2018 to January 2020, excluding secondary osteoporosis and other factors affecting bone metabolism. GE’s LUNAR Prodigy dual-energy X-ray bone density instrument was used to measure the BMD of the lumbar spine 1-4, femoral neck and total hip of those patients. According to the BMD values, patients were divided into the groups of normal bone mass, osteopenia and osteoporosis(OP).Compare the differences in age,disease duration,biochemical indicators,diabetes complications to analyze the influencing factors of bone mineral density in T2DM.SPSS 24.0 statistical software was used for analyzed and P＜0.05 was considered statistically significant. Results The groups of OP had older age, longer duration for T2DM, higher levels of glycosylated hemoglobin, TC,LDL-C and more patients suffer from diabetic microvascular and macrovascular complications（P＜0.05）.The groups of OP had lower HOMA-β level（P＜0.05）. In the logistic regression analysis, older age, longer diabetes duration and higher HbA1c were independent predictors of osteopenia in men with type 2 diabetes in hospitalized. Besides the above factors, the low density lipoprotein cholesterol and combined diabetic microvascular and macrovascular complications were the factors related to the risk of osteoporosis. Conclusion It was found that age, diabetes duration, HbA1c, LDL-C serum and combined diabetic microvascular and macrovascular complications can predict the osteoporosis-risk in men with type 2 diabetes in hospitalized. |