| Type 2 diabetes is a common clinical disease, which causes multiple system complications in the bone, blood vessels and nerve. Osteoporosis is one of its common complications. Patients with type 2 diabetic osteoporosis are mainly manifested with abnormal bone metabolism, increased bone fragility, and prone to fractures. There are many researches on the pathogenesis of type 2 diabetic osteoporosis, including aspects of hyperglycemia, oxidative stress, chronic complications of diabetes, and changes in cytokines and hormone levels, etc. The authors review the latest research in the pathogenesis of type 2 diabetic osteoporosis at home and abroad, aiming to provide reference for the further research and clinical work. |