基于“少火生气”理论探讨糖皮质激素诱导性骨质疏松症的分期论治
Discussion on GIOP based on the theory of mild fire producing Qi
  
DOI:10.3969/j.issn.1006-7108.2021.11.022
中文关键词:  中医药  糖皮质激素  骨质疏松  糖皮质激素诱导性骨质疏松症  治则治法  中医中药
英文关键词:traditional Chinese medicine  glucocorticoids  osteoporosis  GIOP  treatment  traditional Chinese medicine
基金项目:2020年浙江省中医药现代化专项项目(2020ZX009);2018年度浙江省中医药重点研究项目(2018ZZ012);2018年国家自然科学基金(81873129)
作者单位
李少华1 何才剑1 陈天鹏1 房谋昊1 康石发1 孙坚钢1 史晓林2* 1.浙江中医药大学第二临床医学院浙江 杭州 310053 2.浙江中医药大学附属第二医院浙江 杭州 310005 
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中文摘要:
      糖皮质激素诱导性骨质疏松症(glucocorticoid-induced osteoporosis,GIOP)现已在临床上被逐步重视。从中医角度看,根据《黄帝内经》中“壮火食气”的理论,该疾病的主要发病机制为过用具有温热、刚烈性质的糖皮质激素,使人体的脏腑、气血、阴阳受损,不能濡养筋骨,骨失濡养则发为骨质疏松症。笔者对GIOP的病因病机进行了探讨,从“少火生气”理论出发,讨论了GIOP的治则与分期辨证论治,为临床认识和治疗GIOP提供新的思路。
英文摘要:
      Glucocorticoids-induced osteoporosis (GIOP) has been paid more and more attention in the clinics. From the perspective of traditional Chinese medicine, according to the theory of strong fire reduce Qi in Huangdi Neijing, it can be concluded that the main pathogenesis of the disease is excessive use of glucocorticoids, so that the human viscera, Qi and blood, Yin and Yang are damaged, and can not support bones, leading to osteoporosis. This paper discusses the etiology of GIOP, based on the theory of mild fire producing Qi, and discusses the treatment of GIOP and stage syndrome differentiation, providing new ideas for clinical understanding and treatment of GIOP.
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