| Objective To explore the risk factors of primary osteoporosis in China through Meta-analysis, and to provide theoretical basis for the prevention and delay of osteoporosis. Methods We searched CNKI, Wang Fang data, VIP, PubMed, web of science and the Cochrane Library for case control studies on osteoporosis and its risk factors since the database was established. According to the inclusion and exclusion criteria, the data were extracted. Revman 5.4 software was used for Meta-analysis. Results A total of 14 clinical studies were included, and 13 related factors were extracted. Meta analysis showed that the results of BMI and tea drinking were not statistically significant (P>0.05). Age, exercise, calcium intake, dairy products intake, times of pregnancy and childbirth, lactation duration and other influencing factors were statistically significant (P<0.05). Conclusion Exercise, taking calcium and dairy products were the protective factors of primary osteoporosis, while age, smoking, sodium glutamate intake, menopausal years, lactation time, times of pregnancy and labor, systolic blood pressure and fasting blood glucose were the risk factors. The effect of BMI and tea on primary osteoporosis needs further study. |