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| 老年营养风险指数与老年男性2型糖尿病患者骨密度和骨质疏松症的关系 |
| Association between the geriatric nutritional risk index, bone mineral density and osteoporosis in elderly male patients with type 2 diabetes mellitus |
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| DOI：10.3969/j.issn.1006-7108.2021.12.004 |
| 中文关键词: 老年男性2型糖尿病 老年营养风险指数 骨密度 骨质疏松 |
| 英文关键词:elderly male patients with type 2 diabetes mellitus geriatric nutritional risk index bone mineral density osteoporosis |
| 基金项目:长沙市科技局科学技术研究项目（kq1907017）；湖南省卫生健康委科研项目（B2017230）；长沙市科技局科学技术研究项目（kq2004158） |
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| 中文摘要: |
| 目的 探讨老年营养风险指数（geriatric nutritional risk index,GNRI）与老年男性2型糖尿病患者骨密度(bone mineral density, BMD)和骨质疏松症的关系。方法 选取2019年1月至2019年8月在长沙市第一医院内分泌科住院的老年男性2型糖尿病患者216例，根据GNRI值分为降低组(GNRI≤98)和正常组(GNRI>98)，收集患者的一般临床资料，分析GNRI与老年男性2型糖尿病患者骨密度和骨质疏松症的关系。结果 ①与GNRI正常组比较，GNRI降低组股骨颈、全髋BMD更低（P<0.01），骨质疏松症患病率更高（P<0.05）;②GNRI与股骨颈BMD呈正相关（P<0.01）、与全髋BMD呈正相关（P<0.05）;③多元Logistic回归分析GNRI降低是骨质疏松症的独立危险因素（B= – 0.076，P<0.05）。ROC曲线显示包含GNRI的联合指标对老年男性2型糖尿病患者骨质疏松症的预测价值较高。结论 老年男性2型糖尿病患者GNRI与股骨颈、全髋BMD呈正相关，GNRI降低是骨质疏松症的独立危险因素。 |
| 英文摘要: |
| Objective To investigate the association between the Geriatric Nutritional Risk Index, bone mineral density and osteoporosis in elderly male patients with type 2 diabetes mellitus. Methods 216 elderly men with type 2 diabetes mellitus in hospital from January 2019 to August 2019 were selected and divided into the reduced GNRI group (GNRI≤98) and the normal group (GNRI > 98). Clinical data of patients were collected to analyze the relationship between GNRI and bone mineral density and osteoporosis in elderly male patients with type 2 diabetes. Results ① Compared with the normal GNRI group, the reduced GNRI group had a lower femoral neck and total hip BMD（P<0.01）,and a higher incidence of osteoporosis（P<0.05）.② GNRI was positively correlated with femoral neck BMD (P<0.01) and total hip BMD (P<0.05). ③Multiple logistic regression analysis showed that reduced GNRI was an independent risk factor for osteoporosis (B= – 0.076,P<0.05). The ROC curve showed that the combined indexes including GNRI had a higher value in predicting osteoporosis in elderly male patients with type 2 diabetes mellitus. Conclusion GNRI was positively correlated with BMD of femoral neck and total hip in elderly male patients with type 2 diabetes mellitus, and the reduced GNRI was an independent risk factor for osteoporosis. |
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