| Objective To systematically evaluate the application of FRAX (without BMD) to evaluate the fracture in postmenopausal osteoporosis (PMOP). Methods The libraries of CNKI, CBM, VIP, WanFang, PubMed, Embase, and Cochrane were searched systematically, and the methodological quality of the included studies was evaluated, and the Stata 16.0 and Metadiscsoftware were used for meta-analysis. A total of 12 articles and 14 studies were included. Results Meta-analysis showed that the sensitivity of FRAX was 84.68%; the specificity was 63.18%. Combined with SROC curve drawing, the final diagnosis accuracy rate was 85%, P<0.05. and the accuracy was close to that of bone density detection. Among them, the sensitivity of the hip bone to the bone density assessment method is 81.9%; the specificity is 65.02%. When used FRAX evaluation, the final diagnosis accuracy rate was 83%, P<0.05. The sensitivity of the fracture probability of the main site to the bone mineral density assessment method was 73.5%; the specificity is 72.71%. When FRAX was used for evaluation, the accuracy of the diagnosis is 81%, P<0.05. Conclusion FRAX is a reliable fracture assessment method used in women with postmenopausal osteoporosis. |