Objective To analyze the serum level of 25-hydroxyvitamind [25- hydroxyvitamind, 25 (OH) D] in 529 adult females and its influencing factors, so as to provide evidence for the prevention and treatment of osteoporosis, obesity and other diseases. Methods A total of 529 adult woman underwent serum 25 (OH) D level testing in the First Affiliated Hospital of Heilongjiang University of Chinese Medicine from January 2019 to December 2020. 135 of them aged between 19-28 years, 277 between 29-38 years, 54 between 39-48 years, 42 between 49-58 years, and 21 between 59-68 years. Fasting venous blood in the morning was collected and serum 25 (OH) D concentration was determined by enzyme-linked immunoassay. 25 (OH) D<30 nmol/L was considered as vitamin D deficiency. Vitamin D deficiency occurs when serum 25 (OH) D is between 30 and 49.9 nmol/L . Serum 25 (OH) D≥50nmol/L is suitable for vitamin D. Statistical data were collected and basic information such as gender, age and collection time of patients were recorded to analyze the influencing factors of serum 25 (OH) D level. Results The average level of 25 (OH) D in 529 adult women was (19.98±8.58) ng /mL. 19-28 years group was (18.14±8.02) ng /mL, 29-38 years group was (20.44±8.26) ng /mL, 39-48 years group was (20.04±10.14) ng /mL, 49-58 years group was (20.94±8.55) ng /mL, and 59-68 years group was (23.64±10.34) ng /mL. Comparison different age groups (complete random variance analysis one way ANOVA, F=2.88, P<0.05), and the differences were showed statistically significant. The proportion of people aged 19-28 with adequate vitamin D levels is the lowest. By non-parametric test, there was statistical significance among different seasons (α=0.05), summer > autumn > spring > winter. Conclusion Vitamin D deficiency is common in adult females in Harbin, and it is correlated with age and season. |