脾肾-肌骨-线粒体理论探析
Analysis of the theory of spleen-kidney-musculoskeletal-mitochondria
  
DOI:10.3969/j.issn.1006-7108.2021.12.022
中文关键词:  骨质疏松症  脾肾相关  线粒体  中医学
英文关键词:osteoporosis  spleen-kidney related  mitochondria  traditional Chinese medicine
基金项目:国家自然科学基金(81674004,81673786);广东省科技计划项目(2016A020216024);广州中医药大学“双一流”与高水平大学学科协同创新团队重点项目(2021XK21)
作者单位
黄佳纯1,2 黄宏兴1,2* 万雷1,2 林燕平1,2 1.广州中医药大学第三附属医院广东 广州 510000 2.广州中医药大学广东 广州 510000 
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中文摘要:
      黄宏兴教授课题组长期致力于研究骨质疏松症的中医药防治,首次提出脾肾-肌骨-线粒体理论,历年来的相关研究使得该理论逐步完善。本文通过整理相关资料,明确脾肾、肌骨、线粒体三者关系,精炼出该理论的核心内容:骨质疏松与脾肾、线粒体、肌骨关系密切;脾肾-肌骨-线粒体理论基本内容包含了脾肾共司肌骨、线粒体功能与脾肾相通两个核心内容。脾肾-肌骨-线粒体理论是结合中医学中的“脾肾相关”“脾主肌肉”“肾主骨”和现代生物学中的线粒体功能发展而来,其充分运用中医辨证施治原则,在防治骨质疏松症实际应用中发挥着重要作用。本文通过介绍该理论的演变、发展沿革及应用,为骨质疏松症的防治提供实验研究和临床应用相关材料。
英文摘要:
      Professor Huang Hongxing's research group has been committed to the prevention and treatment of osteoporosis with TRADITIONAL Chinese medicine for a long time. He first proposed the theory of spleen and kidney - musculoskeletal - mitochondria, which has been gradually improved by relevant studies over the years.In this paper, the relationship among spleen, kidney, musculoskeletal and mitochondria was clarified by sorting out relevant data, and the core content of the theory was refined: osteoporosis is closely related to spleen, kidney, mitochondria and musculoskeletal;The basic content of the theory of spleen and kidney - musculoskeletal - mitochondria includes two core contents: spleen and kidney share musculoskeletal and mitochondrial function is connected with spleen and kidney.The theory of spleen-kidney-musculobone-mitochondria is developed by combining the "spleen-kidney correlation", "spleen-main muscle" and "kidney-main bone" in Traditional Chinese medicine with the mitochondrial function in modern biology. It makes full use of the principle of syndrome differentiation and treatment in traditional Chinese medicine and plays an important role in the practical application of osteoporosis prevention and treatment. In this paper, the evolution, development and application of the theory are introduced to provide experimental research and clinical application materials for the prevention and treatment of osteoporosis.
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