| Objective To explore the evolution of TCM syndromes in the process of bone mass loss in postmenopausal women, so as to provide theoretical basis for clinical treatment. Methods The clinical data of postmenopausal women were collected with questionnaires and follow-up. The characteristics and evolution of five visceral-organ deficiency syndrome in patients with different follow-up time and the aggravation of bone mass loss were analyzed. Results A total of 175 patients were followed up, and 194 questionnaires were collected, with a follow-up period of 1 year to 7 years and a month. Among those, 97 patients were followed up for less than 3 years and more than 3 years. Analysis of single visceral deficiency syndrome showed that the main types of bone mass loss in postmenopausal women were kidney deficiency, heart deficiency and liver deficiency syndrome. The follow-up time was less than 3 years, the number of patients with liver deficiency syndrome increased significantly after follow-up, and the number of patients with heart deficiency syndrome and lung deficiency syndrome increased significantly during the follow-up. Among the patients with aggravated bone mass loss, the cases of liver deficiency and lung deficiency syndrome also increased significantly during the follow-up, and the difference was statistically significant. Analysis of kidney deficiency and syndrome showed that during the follow-up period of more than 3 years, the number of kidney+heart deficiency, kidney+lung deficiency, and kidney+heart+lung deficiency syndrome increased significantly. Among the patients with aggravated bone mass loss, the cases of kidney+liver deficiency, kidney+heart deficiency, and kidney+lung deficiency syndrome increased significantly. Conclusion With the increase of age and the aggravation of bone mass loss in postmenopausal women, single visceral deficiency may evolve to multiple visceral deficiency syndrome. In a clinical order, many incidence of complex syndromes occurs as kidney and heart deficiency, and follows as kidney and liver deficiency, kidney and lung deficiency, and kidney and heart deficiency and liver deficiency. |