| Objective To analyze the bone mineral content (BMC) results in underweight group (<45 kg), standard weight group (45-60 kg), and overweight group (>60 kg), and to explore the influence of body weight on BMC and its standardization. Methods A total of 290 postmenopausal women aged from 50 to 80 years old were enrolled in this study. They were divided into the underweight group (<45 kg), standard weight group (45-60 kg), and overweight group >60 kg), respectively. BMC and BMD of the lumbar vertebrae 1-4 and femur were measured with DXA and analyzed in different weight groups. Multiple linear regression analysis was performed to explore the influence of age and weight in BMC. Results T value and BMC of the lumbar spine or femoral neck in underweight group were lower than those in standard weight group and overweight group. With the increase of age, BMC of the lumbar vertebrae and femoral neck decreased. With 1-year increase in age, BMC of the lumbar vertebrae and the femoral neck decreased by 0.364 g and 0.031 g, respectively. With the increase of body weight, BMC of the lumbar vertebrae and femoral neck increased. With 1 kg increase in weight, BMC of the lumbar vertebrae and the femoral neck increased by 0.548 g and 0.025 g, respectively. Conclusion There is a significant positive correlation between body weight and BMC in adult women. Therefore, body weight is one of the important indicators in BMC standardization, which can avoid missing diagnosis or misdiagnosis of osteoporosis. |