| Objective To examine the serum levels of 25-hydroxyvitamin D[25(OH)D] in orthopedic outpatients, and to analyze the status of serum vitamin D levels in patients of different gender and age. Methods A total of 2500 patients were enrolled in the orthopedic outpatient of The First Hospital of Kunming from 2018.12 to 2020.12. Their serum levels of 25-hydroxyvitamin D [25(OH)D] were examined with chemiluminescence method (immunoassay). Gender, age, and 25-hydroxyvitamin D were recorded, The level of serum vitamin D was determined according to the value of serum 25(OH)D: (1) deficient: 25(OH)D <20 ng/mL; (2) insufficient: 20 ng/mL ≤ 25(OH)D ≤ 30 ng/mL; and (3) sufficient: 25(OH)D >30 ng/mL. The patients were divided into male and female group according to their gender. According to age, the patients were divided into adolescence group (< 18 years old), youth group (18-43 years old), middle-aged group (44-64 years old), and elderly group (≥65 years old). The relationship between serum vitamin D levels and gender and age in patients of orthopedic outclinic was analyzed. Results There were 1528 cases of vitamin D deficiency (61.1%), 830 cases (33.2%) with vitamin D insufficiency, and 142 cases (5.7%) with adequate vitamin D. The proportion of vitamin D deficiency and insufficiency in the orthopedic outpatient was as high as 94.3%. The mean value of vitamin D in male group and in female group was 20.1±7.0 ng/mL and 18.0±6.9 ng/mL, respectively. There was significant relationship between gender and vitamin D, and the difference was statistically significant (P<0.001). The level of vitamin D in women was less than that in men. The mean value of vitamin D was 17.3±7.2 ng/mL in the adolescence group, 18.4±6.6 ng/mL in the youth group, 18.9±6.8 ng/mL in the middle-aged group, and 18.4±7.5 ng/mL in the elderly group, respectively. There was no correlation between age and vitamin D (P=0.468). Conclusion The level of serum vitamin D is generally deficient and insufficient in orthopedic outpatients. It is one of the important factors of common orthopedic diseases. |