| Objective To investigate the incidence and related risk factors of chronic kidney disease mineral and bone disorder (CKD-MBD) in maintenance hemodialysis (MHD) patients under hypoxic condition at high altitude area. Methods The relevant information of patients from 4 hemodialysis centers in Qinghai province from January 2019 to January 2020 was collected. The patients were divided into the standard group and the non-standard group for comparison according to the Chinese guidelines for the diagnosis and treatment of CKD-MBD published in 2018. The risk factors for CKD-MBD were investigated using multivariate logistic regression method. Results The incidence of CKD-MBD was 92.11%. The levels of calcium, hemoglobin, and albumin in the standard group were higher than those in the non-standard group, and age, dialysis time, phosphorus, parathyroid hormone, β2 microglobulin, alkaline phosphatase, and pre-dialysis urea nitrogen were lower than those in the non-standard group (P<0.05). In Yushu group, age, triglyceride, albumin, diabetes prevalence, and urea reduction rate were lower than those in Xining group, and blood urea nitrogen after dialysis was higher than that in Xining group (P<0.05). Age, dialysis time, calcium, phosphorus, and alkaline phosphatase were risk factors for CKD-MBD. Conclusion CKD-MBD is prevalent in MHD patients at high altitude area. The incidence is up to 92.99%. Age, duration of dialysis, calcium, phosphorus, and alkaline phosphatase are the risk factors. |