| Objective To study whether serum calcium-phosphorus product can be used as a serological index to predict the risk of osteoporotic vertebral compression fractures. Methods This study randomly enrolled 200 elderly patients with osteoporotic vertebral compression fractures from August 2015 to April 2021 in our hospital as the observation group and 200 patients with hip and knee arthroplasty due to femoral head necrosis or osteoarthritis at the same time as the control group. The age, gender, past medical history of hypertension and diabetes, and the first-time biochemical indicators at admission including albumin, urea nitrogen, serum creatinine, serum calcium, serum phosphorus values, etc. were collected for statistical analysis. Results The albumin, serum calcium, serum phosphorus, calcium-phosphorus product, corrected serum calcium and corrected calcium-phosphorus product in the observation group were lower than those in the control group, and the difference was statistically significant (P < 0.05). Multivariate logistic regression analysis showed that low values of serum calcium, serum phosphorus, calcium-phosphorus product, corrected blood calcium, and corrected calcium-phosphorus product all can be considered as risk factors for OVCF patients. ROC curve showed that calcium- phosphorus product and corrected calcium-phosphorus product were effective in predicting the risk of osteoporotic vertebral compression fractures. Among them, the predictive value of calcium phosphorus product was the best, the cut-off point was 29.88, the sensitivity was 0.72 and the specificity was 0.62. The second was the corrected calcium-phosphorus product, the cut-off point was 30.50, the sensitivity was 0.74, and the specificity was 0.62. Conclusion Calcium phosphorus product and corrected calcium phosphorus product can be used as serological indicators to predict the risk of osteoporotic vertebral compression fractures in the elderly. Early clinical interventions targeting this risk factor can further reduce the risk of OVCF. |