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| 东乡族成人低骨量与肌少症相关的肌肉质量下降的相关性研究 |
| Correlation research of low bone mass and skeletal muscle mass loss relate to sarcopenia in Gansu Dongxiang adults |
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| DOI：10.3969/j.issn.1006.7108.2022.04.013 |
| 中文关键词: 低骨量 骨质疏松 肌少症 骨强度指数 骨骼肌质量指数 |
| 英文关键词:low bone mass osteoporosis sarcopenia bone strength index skeletal muscle mass index |
| 基金项目:甘肃省青年科技计划项目（21JR1RA214）；中央高校基本科研项目(31920180027，31920180038)；甘肃省高等学校科研项目(2018B-021 ) |
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| 中文摘要: |
| 目的 分析甘肃省东乡族成人骨量与骨骼肌量变化规律，探讨骨量降低与肌少症相关的肌肉质量下降之间的关系。方法 对甘肃省东乡族432例(男性198例，女性234例)成人骨密度、骨强度及四肢骨骼肌量进行测量及数据分析，不同年龄段多组比较采用单因素方差分析，组间两两比较采用LSD法，相关性分析采用 Pearson 相关分析。结果 ①东乡族成年男性骨强度指数及骨骼肌质量指数峰值出现在40~岁、女性出现在20~岁年龄组。②东乡族成人不同年龄段均出现低骨量与肌少症相关的肌肉质量下降情况。③骨量减少会导致骨强度指数及骨骼肌质量指数降低。④骨量异常情况下肌少症相关的肌肉质量下降明显。⑤骨量降低与年龄、骨强度指数、骨骼肌质量指数显著相关。结论 骨量减少与肌少症相关的肌肉质量下降显著相关，骨量异常是肌少症前期发生的一个危险因素。 |
| 英文摘要: |
| Objective To investigate the change of bone mass and skeletal muscle content in Dongxiang adults and analysis the relationship between low bone mass and muscle mass loss associated with sarcopenia. Methods The bone mineral density, bone strength and human skeletal muscle content were measured from a total of 432(198 males and 234 females) selected cases in Dongxiang. The variance analysis was used for multiple group comparisons in different age groups, LSD method for comparisons between groups, and Pearson correlation analysis for correlation analysis. Results ①The peak of bone strength index and skeletal muscle mass index occurred at 40 years in males and 20 years in females. ②Low bone mass and muscle mass loss associated with sarcopenia emerged in many age groups. ③Bone loss caused the decrease of bone strength index and skeletal muscle mass index. ④Muscle mass loss was distinct in abnormal bone mass condition. ⑤Bone mass loss was associated with age, bone strength index and skeletal muscle mass index significantly. Conclusion Bone mass loss was significantly associated with muscle loss related to sarcopenia, low bone mass is a risk factor for early period of sarcopenia. |
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