| Objective To investigate the changes of age, body mass index (BMI) and body composition in postmenopausal women and their relationship with osteoporosis. Methods The body composition and bone mineral density (BMD) data of 98 postmenopausal women over 45 years collected from the outpatient department of the Third Affiliated Hospital of Guangzhou University of Chinese Medicine from December 2019 to January 2021 were analyzed. According to the age and BMI of the subjects, the body composition of different age and BMI groups were compared.Spearman's rank correlation was used to analyze the effects of age, BMI and body composition on osteoporosis, and multiple linear regression was used to study the influencing factors of BMD and overall bone mineral content(BMC). Results Both BMD(P < 0.001) and BMC(P < 0.05) in each age group decreased with age, while BMC(P <0.05), lean mass(P <0.001) and fat mass(P <0.001) in each BMI group increased with the BMI. Spearman's rank correlation analysis showed that the severity of osteoporosis increased with age (P=0.005,r=0.281). The severity of osteoporosis was decreased with the increase of BMI (P=0.019,r= – 0.237), BMC (P <0.001,r= – 0.719) , lean mass (P=0.014,r= – 0.249) and fat mass（P=0.013,r= – 0.249）.The results of multiple linear regression analysis showed that age was negatively correlated with BMD (P=0.002, B= – 0.004) and BMC (P=0.000, B= – 0.013), while lean mass (P=0.018, B=0.022) and fat mass (P=0.037, B=0.027) were positively correlated with BMC in postmenopausal women.Conclusion Age is a risk factor for osteoporosis in postmenopausal women, while BMI, lean mass and fat mass are protective factors, which can improve the BMD and BMC. |