|
| 绝经后女性躯干肌指数与骨质疏松性椎体骨折的相关性 |
| Association between trunk muscle index and osteoporotic vertebral fracture in postmenopausal women |
| |
| DOI：10.3969/j.issn.1006-7108.2022.07.009 |
| 中文关键词: 躯干肌 骨质疏松 骨质疏松性椎体骨折 绝经后女性 |
| 英文关键词:trunk muscle osteoporosis osteoporotic vertebral fracture postmenopausal women |
| 基金项目: |
|
| 摘要点击次数: 484 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的 探索绝经后女性躯干肌指数与骨质疏松性椎体骨折（osteoporotic vertebral fracture，OVF）的相关性，为骨质疏松性骨折的防治提供新的思路。方法 共纳入424名绝经后女性，其中OVF 212例，骨质疏松症（无OVF）212例，评估其临床因素，测量骨密度、四肢及躯干肌量。采用多元Logistic回归分析躯干肌指数与OVF之间的相关性。结果 与无OVF相比，OVF女性的躯干肌量及躯干肌指数较低（15.99±2.04 vs. 16.72±2.22；6.76±0.72 vs. 7.09±0.85）。调整骨质疏松症的传统危险因素后，躯干肌指数与腰椎骨密度呈正相关（r=0.186，P＜0.001），躯干肌指数是OVF的保护因素（P=0.037，OR=0.684，95% CI：0.478～0.978），基于躯干肌指数，OVF的患病率在4个四分位中呈显著下降趋势。结论 在昆山地区绝经后妇女中，躯干肌指数与腰椎骨密度及OVF密切相关。保持较高的躯干肌指数可能有利于减少OVF的发生。躯干肌指数与腰椎骨密度及OVF的相关性暗示了肌肉与骨骼的内在关联。 |
| 英文摘要: |
| Objective To explore the correlation between trunk muscle index and osteoporotic vertebral fracture (OVF) in postmenopausal women, and to provide new ideas for the prevention and treatment of osteoporotic fracture. Methods A total of 424 postmenopausal women were included, including 212 cases of OVF and 212 cases of osteoporosis (without OVF). Clinical factors were evaluated and bone mineral density, limb and trunk muscle mass were measured. Multiple logistic regression was used to analyze the correlation between trunk muscle index and OVF. Results The trunk muscle mass and trunk muscle index of women with OVF were lower than those without OVF (15.99 ± 2.04 vs. 16.72 ± 2.22; 6.76 ± 0.72 vs. 7.09 ± 0.85). After adjusting for traditional risk factors of osteoporosis, trunk muscle index was positively correlated with lumbar BMD (r=0.186, P<0.001), and trunk muscle index was a protective factor for OVF (P=0.037, OR=0.684, 95% CI: 0.478-0.978). Based on the trunk muscle index, the prevalence of OVF decreased significantly in the four quartiles. Conclusion Trunk muscle index is closely related to lumbar bone mineral density and OVF in postmenopausal women in Kunshan area. Maintaining a high level of trunk muscle index may help to reduce the occurrence of OVF. The correlation between trunk muscle index and lumbar bone mineral density and OVF suggests the internal relationship between the muscle and the bone. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |