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| 绝经后女性肌少症和骨质疏松症对平衡能力的影响 |
| Effect of sarcopenia and osteoporosis on balance in postmenopausal women |
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| DOI：10.3969/j.issn.1006-7108.2022.08.003 |
| 中文关键词: 绝经后女性 肌少症 骨质疏松症 肌少-骨质疏松症 平衡 |
| 英文关键词:postmenopausal women sarcopenia osteoporosis osteosarcopenia balance |
| 基金项目:国家“主动健康和老龄化科技应对”重点专项（2018YFC2000600）；北京市教育委员会科研计划项目（KM201910029002） |
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| 中文摘要: |
| 摘要：目的 探讨绝经后女性肌少症和骨质疏松症对平衡能力的单独及联合影响。方法 从北京市社区招募符合要求的绝经后女性332人，分为正常组238人、肌少症组27人、骨质疏松症组44人、肌少-骨质疏松症组23人。根据亚洲肌少症工作组（AWGS）的诊断标准诊断肌少症，采用世界卫生组织（WHO）的骨质疏松症诊断标准诊断骨质疏松症，采用闭眼单脚站立时间（SST）评估静态平衡能力，通过定时起立-行走测试（TUGT）评估动态平衡能力，采用二元Logistic回归分析肌少症及骨质疏松症与平衡不良之间的关系。结果 肌少症和肌少-骨质疏松症患者静态和动态平衡不良发生率显著高于骨质疏松症患者和正常人（P<0.05），骨质疏松症患者与正常人静态和动态平衡不良发生率无显著差异（P>0.05）。二元Logistic回归分析结果显示，肌少症和肌少-骨质疏松症是静态平衡不良（OR=5.747, 95% CI: 1.871~17.651, P=0.002；OR=6.989, 95% CI: 1.902~25.685, P=0.003）的独立危险因素，也是动态平衡不良的独立危险因素（OR=6.843, 95% CI: 2.671~17.535, P=0.000；OR=9.779, 95% CI: 3.317~28.836, P=0.000），且患有肌少-骨质疏松症者静态平衡不良和动态平衡不良发生风险显著高于仅患有肌少症者；单独患有骨质疏松症对静态和动态平衡不良发生风险均无显著影响（P>0.05）。结论 患肌少症或肌少-骨质疏松症都会增加绝经后女性静态和动态平衡不良的发生风险；肌少症和骨质疏松症对绝经后女性静态平衡不良和动态平衡不良的发生具有协同效应。 |
| 英文摘要: |
| Abstract: Objective To investigate the effect of sarcopenia and osteoporosis on balance ability in postmenopausal women. Methods A total of 332 postmenopausal women were recruited in Beijing community, including 238 patients in normal group, 27 in sarcopenia group, 44 in osteoporosis group and 23 in osteosarcopenia group. Sarcopenia was diagnosed according to the diagnostic criteria of Asian Sarcopenia Working Group (AWGS). The world Health Organization (WHO) osteoporosis diagnostic criteria were used to diagnose osteoporosis. Static balance ability was evaluated by stork stand test (SST) and dynamic balance ability was evaluated by time up and go test (TUGT). Binary logistic regression was used to analyze the relationship between sarcopenia, osteoporosis and poor balance. Results Poor static balance and poor dynamic balance was significantly higher in sarcopenia group and osteosarcopenia group than in osteoporosis group and normal group (P>0.05), there was no significant difference in the incidence of static and dynamic poor balance between osteoporosis group and normal group (P>0.05). Binary Logistic regression analysis showed that sarcopenia (OR=5.747, 95% CI: 1.871-17.651, P=0.002) and osteosarcopenia (OR=6.989, 95% CI: 1.902-25.685, P=0.003) was an independent risk factor for static and dynamic poor balance (OR=6.843, 95% CI: 2.671-17.535, P=0.000; OR=9.779, 95% CI: 3.317-28.836, P=0.000), and the risk of static and dynamic poor balance in patients with osteosarcopenia was significantly higher than that in patients with sarcopenia alone. Osteoporosis alone had no significant effect on the risk of static or dynamic poor balance(P>0.05). Conclusions Sarcopenia or osteosarcopenia increases the incidence of static and dynamic poor balance in postmenopausal women. Sarcopenia and osteoporosis have a synergistic effect on static and dynamic poor balance in postmenopausal women. |
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