| Abstract: The prevention and treatment of osteoporosis with traditional Chinese medicine (TCM) is a hot topic. Clinically, good results have been obtained through the treatment from the viewpoint of spleen and kidney. The research on its mechanism have been gradually carried out. Spleen deficiency is the basis of osteoporosis. Nourishing qi to invigorating spleen therapy aims at enriching muscles and bones, which may relieve clinical symptoms, improve bone mineral density, and regulate bone metabolism balance. More and more basic research show that nourishing qi to invigorating spleen therapy plays an important role in regulating endocrine, nervous, motor, digestion, and circulation systems for anti-osteoporosis purpose. In order to explore the clinical value and scientific connotation of treating osteoporosis from the viewpoint of spleen, the authors summarize the curative effect and possible mechanism of nourishing qi to invigorating spleen therapy on osteoporosis from the aspects of traditional Chinese medicine classical theory, clinical research, and basic experiments, in order to broaden the research ideas of TCM in the prevention and treatment of osteoporosis. |