|
| 女性原发性骨质疏松症与中医肝脾亏虚的关联分析 |
| Correlation analysis between female primary osteoporosis and deficiency of liver and spleen in traditional Chinese medicine |
| |
| DOI：10.3969/j.issn.1006.7108.2022.10.012 |
| 中文关键词: 脾虚证 肝虚证 原发性骨质疏松症 相关性 |
| 英文关键词:spleen deficiency syndrome liver deficiency syndrome primary osteoporosis correlation |
| 基金项目:国家自然科学基金(81674007，81873323) |
|
| 摘要点击次数: 261 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的 探讨女性原发性骨质疏松症（primary osteoporosis，POP）与中医肝脾亏虚的关联性，为运用健脾、补肝法防治POP提供临床依据。方法 对近15年来在我院骨质疏松专科门诊检测的女性3 350例进行回顾性研究，结合问卷调查、骨密度检测和中医辨证，采用SPSS统计软件分析。结果 ①纳入2 692例，其中，POP组934例，无POP组1 758例，POP组中肝虚418例（44.80 %）、脾虚159例（17.00 %），无POP组中肝虚803例（45.70 %）、脾虚232例（13.20 %），脾虚在两组间的差异有统计学意义（P＜0.05），肝虚在两组间差异无统计学意义（P＞0.05）；②与无POP妇女相比，女性POP与脾虚、肝脾俱虚存在相关性（P＜0.05）；③二分类Logistic回归结果显示女性POP的危险因素包括年龄、脾虚（P＜0.05）。结论 肝脾亏虚是女性POP的重要因素；脾虚是女性POP发病的危险因素；肝虚在绝经后及老年妇女中发生率均较高，但不随着骨量丢失而进一步增加。 |
| 英文摘要: |
| Objective To explore the correlation between female primary osteoporosis(POP) and deficiency of liver and spleen in traditional Chinese medicine, and To provide clinical basis for the prevention and treatment of POP by strengthening the spleen and tonifying the liver. Methods A retrospective study was carried out on 3350 women ,who test in the POP specialist clinic of our hospital in recent 15 years. Combined with questionnaire survey, bone mineral density test and TCM syndrome differentiation, then SPSS statistical software was used for analysis. Results ① 2692 cases were included, including 934 cases in the POP group, 1758 cases in the non POP group, 418 cases of liver deficiency (44.80%), 159 cases of spleen deficiency (17.00%) in the POP group, 803 cases of liver deficiency (45.70%) and 232 cases of spleen deficiency (13.20%) in the non POP group. The difference of spleen deficiency between the two groups was statistically significant (P＜0.05), and there was no significant difference in liver deficiency between the two groups (P＞0.05). ② Compared with women without POP, POP in women was correlated with spleen deficiency and deficiency of both liver and spleen (P＜0.05); ③Binary logistic regression showed that the risk factors of female POP included age and spleen deficiency(P＜0.05). Conclusion Deficiency of liver and spleen is an important factor in the pathogenesis of female POP; Spleen deficiency is the risk factor of female POP; The incidence of liver deficiency is higher in postmenopausal and elderly women, but it does not increase with bone loss. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |