骨质疏松高风险人群中医症状辨识工具的初步探析
Preliminary analysis of TCM symptom identification tools in high risk population of osteoporosis
  
DOI:10.3969/j.issn.1006.7108.2022.10.018
中文关键词:  骨质疏松症  高风险人群  中医症状  筛查工具
英文关键词:osteoporosis  high-risk population  TCM syndromes  screening tools
基金项目:国家重点研发计划中医药现代化研究专项(骨质疏松高风险人群中医“治未病”干预技术示范研究)(2018YFC1704703);北京中医药大学高层次人才科研启动项目(2021-XJ-KYQD-001)
作者单位
曾祥荣1,2 赵伟1 王荣田1 陈强龙2 孙继高3,5 何海军3 谭彪3 奚向宇4 陈卫衡1* 1.北京中医药大学第三附属医院北京 100029 2.贵州中医药大学贵州 贵阳 550005 3.中国中医科学院望京医院北京 100102 4.北京市西城区广外医院北京 100080 5.北京中医药大学东方医院北京 100078 
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中文摘要:
      目的 通过应用骨质疏松高风险人群中医症状辨识工具,探讨不同骨量人群中医症状特点分布,为骨质疏松高风险人群的中医辨识提供依据。方法 于2020年9月至2021年6月招募受试者,收集受试者的临床资料以及骨质疏松高风险人群中医症状辨识问卷结果,录入建立数据库,采用卡方检验对中医症状发生频率进行比较,分析不同骨量人群中医症状分布差异。结果 ①对符合标准的293例受试者的资料和问卷结果进行分析,其中骨量减少124例,骨量正常137例,骨质疏松症32例。②其中腰膝酸软(40.32 % vs 27.74 %)、身高变矮(52.42 % vs 36.50 %)、下肢拘挛(35.48 % vs 17.52 %)、倦怠乏力(29.84 % vs 18.25 %)、多梦易惊(27.42 % vs 14.60 %)、失眠(37.10 % vs 21.90 %)、耳鸣(31.45 % vs 17.52 %)、健忘(54.03 % vs 32.85 %)、口燥咽干(39.52 % vs 25.55 %)、视物模糊(45.16 % vs 29.93 %)、目睛干涩(43.55 % vs 27.74 %)共11个中医症状在骨量减少组中出现的频率较骨量正常组高,差异具有统计学意义;③腰膝酸软(40.32 % vs 56.25 %)、畏寒(40.32 % vs 56.25 %)、耳鸣(31.45 % vs 46.88 %)、腰痛(48.39 % vs 62.5 %)、目眩(23.39 % vs 37.5 %)、发脱齿摇(29.84 % vs 43.75 %)、多梦易惊(27.42 % vs 40.63 %)、目睛干涩(43.55 % vs5 6.25 %)、夜尿多(21.77 % vs3 4.38 %)、纳呆(8.06 % vs 18.75 %)、足跟痛(14.52 % vs 25.00 %)、手足烦热(15.32 % vs 25.00 %)、毛发枯槁(6.45 % vs 15.63 %)、周身痛(19.35 % vs 28.13 %)、易怒(25.81 % vs 34.38 %)、体重减轻(8.06 % vs15.63 %)、背痛(37.9 % vs 43.75 %)、遇寒痛甚(37.9 % vs 43.75 %)、头晕(25.81 % vs 31.25 %)、下肢拘挛(35.48 % vs 40.63 %)、下肢困重(33.06 % vs 37.50 %)、健忘(54.03 % vs 56.25 %)、面黄肌瘦(4.03 % vs 6.25 %)、肢体麻木(17.74 % vs 18.75 %)共25个中医症状在骨量减少组中出现的频率较骨质疏松症组低,但差异无统计学意义;而气短(20.97 % vs 46.88 %)在骨量减少组中出现频率较骨质疏松症组低,差异具有统计学意义。结论 不同骨量人群发生的中医症状频率和频数不同,且在骨量正常、骨量减少到骨质疏松症的不同人群中呈现中医症状逐渐增多的趋势,可以用中医症状来辨识骨质疏松高风险人群,中医症状辨识工具对筛检骨质疏松高风险人群具有一定价值。
英文摘要:
      Objective To explore the distribution of TCM symptoms in people with different bone masses by TCM Symptoms Identification tools in High-risk Population of Osteoporosis, and to provide clinical evidence for TCM identification of people at high risk of osteoporosis. Methods This research group recruited subjects from September 2020 to June 2021, collected clinical data of subjects and the results of the TCM symptom identification questionnaire for people at high risk of osteoporosis, entered the database, and used the chi-square test to determine the occurrence of TCM symptoms The frequency is compared, and the differences in the distribution of TCM symptoms among people with different bone masses are analyzed. Results ①The data of 293 subjects and the results of the questionnaire were analyzed. Among them, 124 had reduced bone mass, 137 had normal bone mass, and 32 had osteoporosis. ②Among them, the waist and knees are sore (40.32% vs 27.74%), the height becomes shorter (52.42% vs 36.50%), lower extremity spasm (35.48% vs 17.52%), fatigue Fatigue (29.84% vs 18.25%), dreaminess (27.42% vs 14.60%), insomnia (37.10% vs 21.90%), tinnitus (31.45% vs 17.52%), forgetfulness (54.03% vs 32.85%), dry mouth and dry throat (39.52% vs 25.55%), blurred vision (45.16% vs 29.93%), dry eyes (43.55% vs 27.74%), a total of 11 TCM symptoms appear more frequently in the osteopenia group than in the normal bone mass group,with statistical differences.③ Soreness of the waist and knees (40.32% vs 56.25%), chills (40.32% vs 56.25%), tinnitus (31.45% vs 46.88%), low back pain (48.39% vs 62.5%), dizziness (23.39% vs 37.5%), loss of teeth (29.84% vs 3.75%), dreaminess (27.42% vs 40.63%), dry eyes (43.55% vs 56.25%), excessive nocturia (21.77% vs 34.38%), anorexia (8.06% vs 18.75%), heel pain (14.52% vs 25%), irritated hands and feet (15.32% vs 25%), withered hair (6.45% vs 15.63%), body pain (19.35% vs 28.13%), irritability (25.81% vs 34.38%), weight loss (8.06% vs 15.63%), back pain (37.9% vs 43.75%), severe cold pain (37.9% vs 43.75) %), dizziness (25.81% vs 31.25%), lower limb spasm (35.48% vs 40.63%), lower limb sleepiness (33.06% vs 37.5%), forgetfulness (54.03% vs 56.25%), yellow facial muscle thinness (4.03% vs 6.25%), limb numbness (17.74% vs 18.75%), a total of 25 TCM symptoms appeared in the osteopenia group less frequently than in the osteoporosis group, but did not reach a statistical difference; The frequency of shortness of breath (20.97% vs 46.88%) in the osteopenia group is lower than that in the osteoporosis group, which is statistically different. Conclusion People with different bone mass have different frequency and frequency of TCM symptoms, and there is a trend of increasing TCM symptoms in different people with normal bone mass and bone mass reduction to osteoporosis. TCM symptoms can be used to identify high risk of osteoporosis. For the population, TCM symptom identification tools have certain value for screening high-risk populations of osteoporosis.
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