运动疗法防治骨质疏松症机制的研究进展
Research progress in the mechanism of exercise therapy in the prevention and treatment of osteoporosis
  
DOI:10.3969/j.issn.1006.7108.2022.10.028
中文关键词:  骨质疏松症  运动疗法  机制
英文关键词:osteoporosis  exercise therapy  mechanism
基金项目:中国中医科学院科技创新工程项目(C12021A03320)
作者单位
佟喆 张振南 于潼* 中国中医科学院广安门医院北京 100053 
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中文摘要:
      骨质疏松症是一类全身性、代谢性骨病,表现为持续骨量减少、骨组织微结构退变,骨的强度降低,继发骨脆性增加,引起疼痛和驼背等症状,并能极易出现病理性骨折的疾病。合理适当的运动有助于改善骨质流失而防治骨质疏松症。为更加清晰地认知运动疗法防治骨质疏松的理论基础,以帮助指导临床制定更为合理的运动治疗处方,更好发挥其防治骨质疏松症的优势,本文详细介绍了中西运动疗法在防治骨质疏松症的作用机制。例如西医注重运动机械应力对骨骼的效应作用、运动对钙的调节效应作用、运动诱导细胞调节因子、激素的变化对骨代谢的作用、运动对骨代谢信号通路的调节作用以及其他新陈代谢作用;中医则认为其病因病机主要是与肾、脾、肝三脏的关系,传统中医导引运动疗法防治骨质疏松的作用机制正是通过功法由外到内的调理三脏。中医运动疗法-导引功法与西医运动疗法比较更适合在我国的推广,临床应用中更具有独特的优势,以发挥其“简、便、廉、效”的目的。
英文摘要:
      Osteoporosis is a systemic and metabolic bone disease, characterized by continuous bone loss, bone microstructure degeneration, bone strength reduction, secondary bone fragility increase. It may cause pain and humpback and other symptoms, and pathological fracture disease. Reasonable and appropriate exercise improves bone loss and prevents osteoporosis. In order to better understand the theoretical basis of exercise therapy in the prevention and treatment of osteoporosis, to help guide the clinical formulation of more reasonable exercise therapy prescription, and to better play its advantage in the prevention and treatment of osteoporosis, this paper introduces the mechanism of Chinese and Western exercise therapy in the prevention and treatment of osteoporosis in detail. For example, Western medicine pays attention to the effect of mechanical stress on bone, the regulatory effect of exercise on calcium, the effect of exercise-induced cell regulatory factors, the effect of hormone changes on bone metabolism, and the regulatory effect of exercise on bone metabolism signal pathway and other metabolic effects. Traditional Chinese medicine (TCM) believes that the etiology and pathogenesis of osteoporosis are mainly related to the kidney, spleen, and liver. The mechanism of exercise therapy guided by traditional Chinese medicine to prevent and treat osteoporosis is to regulate the three organs from the outside to the inside. Compared with Western medicine exercise therapy, TCM exercise therapy-guidance method is more suitable for promotion in our country, and has unique advantage in clinical application, so as to play its purpose of simplicity, convenience, low cost, and efficiency.
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