| Estrogen is a steroid hormone with a wide range of functions and effects in the body. In addition to regulating the function of female reproductive organs, it can also target other organs and tissues that express estrogen receptors, including the cardiovascular system, bones, and skeletal muscle etc. With the growth of women's age, estrogen deficiency can lead to a decline in skeletal muscle mass, which seriously affects the health and life of the elderly. In recent years, the protective effect of estrogen on skeletal muscle has gradually been paid more and more attention. At present, studies have shown that estrogen receptor (ER) is closely related to skeletal muscle weakness and other diseases, and ER can mediate PI3K/AKT signaling pathway and many other diseases. The pathway plays a role in protecting skeletal muscle and effectively prevents skeletal muscle degeneration. |