| Pregnancy and lactation related osteoporosis is a rare secondary osteoporosis,which usually occurs in late pregnancy and early lactation. Due to its low incidence and its specific timing, relatively limited diagnostic tools, and the fact that most reports in the literature are case by case or general descriptions of the disease state, guidelines and consensus for its management and diagnosis have not been developed. Due to the self-limiting nature of pregnancy and lactation-related osteoporosis, some patients experience spontaneous improvement in bone mineral density after pregnancy and lactation. Therefore, firm recommendations on how to treat patients with this disease have not been clearly formulated, and Calcitonin, Bisphosphonates, Desuzumab and Teriparatide have all been used in individual patients, but the results of treatment have been mixed and there is no extensive objective data to provide feedback on the long-term effects of treatment; therefore, the exploration of Pregnancy and lactation-related osteoporosis remains to be continued, and it is expected that a consensus will be formed and safer drugs will be developed to treat this disease in the future. |