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| 肌少-骨质疏松症研究现状及展望 |
| Research status and prospect in osteosarcopenia |
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| DOI：10.3969/j.issn.1006-7108.2023.05.011 |
| 中文关键词: 肌少-骨质疏松症 肌少症 骨质疏松症 骨量减少 |
| 英文关键词:osteosarcopenia sarcopenia osteoporosis osteopenia |
| 基金项目:国家自然科学基金项目(81973886，82174395)；2022年广东省研究生教育创新计划项目（2022XSLT013）；黄宏兴广东省名中医传承工作室（粤中医办函[2018]5号）；广州中医药大学“双一流”与高水平大学学科协同创新团队重点项目(2021XK21) |
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| 中文摘要: |
| 骨质疏松症和肌少症作为增龄性骨骼肌肉疾病，与一系列不良身体和代谢结果相关，两者共存将形成肌少-骨质疏松症，有学者称之为21世纪的老年病巨头。肌少-骨质疏松症是一种多因素、多病因的进行性疾病，其病理生理机制可能与衰老导致的遗传、机械、内分泌紊乱相关，出现肌肉或骨骼问题的患者均应进行全面的筛查与评估以及早进行运动锻炼、营养支持、药物治疗等干预，以降低共病状态下的众多负面影响。目前对于肌少-骨质疏松症研究才刚刚起步，对新的综合征的认识还需更多探索和思考，“肌为骨用、肌骨并重”应是肌肉骨骼疾病研究和发展的重要思路。 |
| 英文摘要: |
| Osteoporosis and sarcopenia, as age-related musculoskeletal diseases, are associated with a series of adverse physical and metabolic outcomes. The coexistence of the two forms osteosarcopenia. According to some scholars, it is the geriatric giant of the 21st century. Sarcopenia-osteoporosis is a progressive disease with multiple factors and multiple etiologies. Its pathophysiological mechanism may be related to genetic, mechanical, and endocrine disorders caused by aging. Patients with muscular or skeletal problems should undergo comprehensive screening and evaluation, as well as early interventions such as exercise, nutritional support, and drug therapy, which may reduce the negative effects of comorbidity. At present, the research on osteosarcopenia has just started, and the understanding of the new syndrome needs more exploration and thinking. Muscle serving for bone and musculoskeletal theory should be an important idea for the research and development of musculoskeletal diseases. |
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