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| 中医“骨肉不相亲”理论分析肌肉与老年骨质疏松性骨折的关系 |
| The role of muscles in the treatment of osteoporotic fractures in the elderly based on the disharmony between bone and muscle theory in traditional Chinese medicine |
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| DOI：10.3969/j.issn.1006-7108.2023.05.022 |
| 中文关键词: 骨肉不相亲 肌肉 骨质疏松性骨折 骨修复 中医中药 |
| 英文关键词:disharmony between bone and muscle muscle osteoporotic fracture bone repair traditional Chinese medicine |
| 基金项目:国家重点研发计划项目（2018YFC1704300）；国家自然科学基金项目（81973883，81730107）；上海市自然科学基金项目（19ZR1458000）；上海市科委中药创新与传承领域项目（20S21902000） |
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| 中文摘要: |
| 骨质疏松性骨折（osteoporotic fracture，OPF）又称脆性骨折，是一种高发于老年群体的病理性骨折，由于其致死致残率极高，严重影响老年患者的生存质量，该病的治疗已引起社会广泛关注。研究发现老年骨质疏松性骨折患者多存在肌肉与骨骼失衡的病理关系，而这和中医学“骨肉不相亲”理论高度契合。肌肉与骨骼解剖上毗邻，越来越多的证据显示，肌肉参与骨修复促进骨健康。因此，该文在“骨肉不相亲”理论指导下，综述肌肉在治疗老年骨质疏松性骨折中作用机制的最新研究进展，旨在丰富“骨肉不相亲”理论的现代科学内涵，为OPF的防治提供新思路、新方案。 |
| 英文摘要: |
| Osteoporotic fracture (OPF), also known as fragility fracture, is a pathological fracture with a high prevalence in the elderly population, which seriously affects the quality of life of elderly patients due to its high mortality and disability rate. Studies have shown that most elderly patients with osteoporotic fractures have a pathological relationship between muscle and bone imbalance, which is highly compatible with the disharmony between bone and muscle theory in traditional Chinese medicine. Muscles are anatomically adjacent to bones. There is increasing evidence showing that muscles are involved in bone repair to promote bone health. Therefore, under the guidance of the disharmony between bone and muscle theory, the paper reviews the latest research progress in the mechanism of muscle action in the treatment of osteoporotic fractures in the elderly, aiming to enrich the modern scientific connotation of the theory of disharmony between bone and muscle and to provide new ideas and solutions for the prevention and treatment of OPF. |
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