氧化应激在骨质疏松症与肩袖损伤共病机制中的研究 进展
Research progress of oxidative stress in the pathogenesis of osteoporosis and rotator cuff injury
  
DOI:10.3969/j.issn.1006-7108.2023.05.029
中文关键词:  骨质疏松症  肩袖损伤  共病  氧化应激
英文关键词:osteoporosis  shoulder sleeve damage  comorbidity  oxidative stress
基金项目:苏州市临床重点病种诊疗技术专项项目 (LCZX202127);昆山市中医医院金杏优才项目(03RCZC?25)
作者单位
汪青 钱胤华 黄昊强 钱平康 徐锋∗ 昆山市中医医院骨伤中心江苏昆山215300 
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中文摘要:
      骨质疏松症和肩袖损伤共病在临床上较为常见,两者具有一些共同的危险因素及病理机制。氧化应激是指活性氧的生 成与消除失衡,过量的活性氧导致细胞损伤及凋亡,影响细胞功能并引发疾病。研究发现,氧化应激在骨质疏松症及肩袖损 伤的病理机制中扮演着重要的角色。本文就氧化应激在骨质疏松症与肩袖损伤共病机制中的作用作一综述,旨在为肩袖损 伤与骨质疏松症的共病治疗提供新的思路。
英文摘要:
      Osteoporosis and rotator cuff injury are common in clinic, and they have some common risk factors and pathological mechanisms. Oxidative stress refers to the imbalance between the generation and elimination of reactive oxygen species. Excessive reactive oxygen species lead to cell damage and apoptosis, affect cell function and cause disease. It has been found that oxidative stress plays an important role in the pathogenesis of osteoporosis and rotator cuff injury. This article reviews the role of oxidative stress in the pathogenesis of the comorbidity of osteoporosis and rotator cuff injury, in order to provide new ideas for the treatment of the comorbidity of rotator cuff injury and osteoporosis.
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