肠道菌群在HIV相关骨质疏松症中的影响
Exploring the impact of intestinal flora in HIV-associated osteoporosis
  
DOI:10.3969/j.issn.1006-7108.2023.07.030
中文关键词:  HIV  骨质疏松症  肠道菌群
英文关键词:HIV  osteoporosis  intestinal flora
基金项目:国家自然科学基金(81960903)
作者单位
管显师1 林宗汉2* 张鸿升1 刘振威1 曹丽1 叶欣鑫1 1. 广西中医药大学广西 南宁 530000 2. 广西中医药大学附属瑞康医院空港院区广西 崇左 532200 
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中文摘要:
      HIV/AIDS患者在HIV、ART、免疫功能改变等多种因素影响下,常导致骨骼、心血管、消化等系统疾病,骨质疏松症是其常见并发症之一,目前发病机制尚不完全明晰。随着对肠道微生态的不断深入研究,肠道菌群的失调被认为是骨质疏松症的发病机制之一。因此,本文拟对HIV/AIDS患者肠道菌群及肠道菌群失调致骨质疏松的发病机制相关研究进展进行概述,以期能为HIV相关骨质疏松症的治疗和预防提供新思路。
英文摘要:
      It has been found that people living with HIV/AIDS (hereafter referred to as HIV/AIDS patients) often suffer from a combination of osteoporosis, the pathogenesis of which is still unclear. The pathogenesis of osteoporosis is still unknown. With the continuous research on intestinal microecology, the dysbiosis of intestinal flora is considered to be one of the pathogenic mechanisms of osteoporosis. Therefore, this paper provides an overview of the research progress on the pathogenesis of osteoporosis in HIV/AIDS patients with intestinal flora and intestinal dysbiosis, with a view to providing new ideas for the treatment and prevention of HIV-related osteoporosis.
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