| Objective To compare and analyze the value of FRAX (excluding BMD model), BMD, BMI and OSTA in predicting the risk of osteoporosis in peri- and postmenopausal women in the southern suburbs of Beijing. Methods 3253 peri- and postmenopausal women who underwent bone mineral density examination in Daxing District Hospital of Integrated traditional Chinese and Western Medicine from January 2017 to June 2022 were selected. The data of age, height, weight, and bone mineral density T value were collected, and the differences of FRAX (excluding BMD model), BMD, BMI and OSTA among different age groups and different bone mass were analyzed. The ROC curves of different indexes for the diagnosis of osteopenia or osteoporosis were drawn, and the prediction accuracy of each index was compared. Results ①With the increase of age, BMD and OSTA decreased, FRAX-MOF and FRAX-HF increased. ②The smaller the bone mass, the lower the BMD and OSTA, the higher the FRAX-MOF and FRAX-HF. ③ The AUC values of FRAX-MOF and FRAX-HF in the diagnosis of osteoporosis were 0.811 and 0.810 respectively, which was better than that of OSTA (AUC=0.799) (P < 0.001). ④ The AUC values of FRAX-MOF and FRAX-HF in the diagnosis of osteopenia were 0.770 and 0.767 respectively, which was better than that of OSTA (AUC=0.748) (P < 0.001). The specificity of OSTA index was higher (83.0%) and the critical value was 0.10. Conclusion The FRAX tool without BMD is better than OSTA in the diagnosis of OP in peri- and postmenopausal women. However, OSTA is simpler and has better diagnostic efficacy, so it is more suitable for community or remote areas. OSTA 0.1 can be used as the threshold for early intervention. |