| Objective To investigate the relationship between hemoglobin (HGB) and osteoporosis fractures in elderly patients. Methods A total of 324 hospitalized patients over 50 years old, who were diagnosed with spinal fracture in the Second Department of orthopedics of Guangzhou University of Chinese Medicine from January 2021 to May 2022, were selected. Medical data such as bone mineral density (BMD) and HGB were collected from the electronic medical records. Results In men, anemia incidence increased significantly and HGB decreased significantly (P<0.001). No association was found in women. Classified by anemia, BMD decreased in both genders due to anemia (P<0.01). In men, HGB was associated with L1-4 BMD (r=0.466, P<0.001), left femoral neck BMD (r=0.424, P<0.001), and left total hip BMD (r=0.469, P<0.001). In women, HGB was associated with L1-4 BMD (r=0.199, P=0.002), left femoral neck BMD (r=0.326, P<0.001), and left total hip BMD (r=0.341, P<0.001). Binary logistic regression found an association between HGB and osteoporosis in men (OR=0.956, 95% CI:0.917-0.997, P=0.035). No association was found in women. Conclusion HGB is related to BMD. Lower HGB may cause a high risk of osteoporosis fracture in elderly men. |