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| 从“虚、瘀、痰、郁”探讨绝经后膝骨关节炎合并骨质疏松病机特点 |
| The etiology and pathogenesis of postmenopausal knee osteoarthritis complicated with osteoporosis discussed from weakness, stasis, phlegm, and depression |
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| DOI：10.3969/j.issn.1006-7108.2024.02.024 |
| 中文关键词: 绝经后膝骨关节炎合并骨质疏松症 病因病机 中西医结合 |
| 英文关键词:postmenopausal knee osteoarthritis complicated with osteoporosis etiology and pathogenesis integrated Chinese and Western medicine |
| 基金项目:浙江省中医药现代化专项项目（2021ZX009）；浙江省高层次卫生创新人才培养对象；国家中医临床研究基地支撑学科（2020-JDXK-ZC01）；浙江省“十三五”重点专科建设项目（外科-运动创伤科） |
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| 中文摘要: |
| 膝骨关节炎（ knee osteoarthritis，KOA）合并骨质疏松症（osteoporosis，OP）是一种好发于绝经后女性的慢性退行性骨病，也是影响中老年女性生活质量和心理健康的重要危险因素。目前西医关于KOA合并OP的发病机制尚不明确，且二者相关性也存在较大争议。本文从KOA与OP的病理特点与绝经后女性生理特点出发，将绝经后KOA合并OP的中医病机特点及演变规律总结为“虚、瘀、痰、郁”四个方面。同时本文依据此理论把与KOA合并OP相关的现代医学进展及科学研究进行了梳理，探求中医病机特点与西医病理机制的相通之处，以期更为全面且科学地理解绝经后KOA合并OP的病机本质和发生发展规律。 |
| 英文摘要: |
| Knee osteoarthritis (KOA) complicated with osteoporosis (OP) is a chronic degenerative bone disease commonly found in postmenopausal women. Also, it’s an important risk factor affecting the quality of life and mental health of middle-aged and elderly women. Currently, the etiology and pathogenesis of KOA complicated with OP are not clear in Western medicine, and the correlation between KOA and OP is also controversial. Based on the pathological characteristics of KOA and OP and the physiological characteristics of postmenopausal women, this paper summarized the etiology and pathogenesis of KOA complicated with OP into four aspects: Weakness, Stasis, Phlegm, and Depression. Besides, this paper sorted out the progress of modern medicine and original research related to KOA complicated with OP based on these four aspects mentioned above and explored the similarities of etiology and pathogenesis of KOA complicated with OP between traditional Chinese medicine and Western medicine. Therefore, it’s better to understand the pathogenesis and development of postmenopausal KOA complicated with OP more comprehensively and scientifically. |
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