|
| 倾向性评分匹配的兰州市老年住院患者的肌少症危险因素分析 |
| Analysis of risk factors of sarcopenia in elderly inpatients in Lanzhou with propensity score matching |
| |
| DOI：10.3969/j.issn.1006-7108.2024.03.001 |
| 中文关键词: 倾向性评分匹配 肌少症 身体成分 危险因素 |
| 英文关键词:propensity score matching sarcopenia body composition risk factors |
| 基金项目:甘肃省自然科学基金项目（22JR5RA925） |
|
| 摘要点击次数: 22 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的 基于倾向性评分匹配分析兰州市60周岁及以上老年住院患者的肌少症危险因素，为该类人群肌少症的筛查与预防提供依据。方法 选择兰州大学第一医院老年病科二病区60周岁及以上的住院患者，经肌少症筛查，按是否合并高血压、冠心病、脑梗死、糖尿病，通过1∶1倾向性评分匹配（PSM），分为肌少症组与非肌少症组。匹配后对两组人口基线资料（年龄、性别）、身体成分（体质指数、身高、体重、去脂体重、腰臀比、体脂百分比等）、生化指标进行单因素分析比较，利用多因素Logistic回归分析法分析兰州老年岁住院患者肌少症发生的危险因素。结果 接受肌少症筛查的患者共743例，183例确诊为肌少症，肌少症检出率为25.49 %，肌少症组年龄、总四碘甲状腺原氨酸、中性粒细胞百分比、肌酐、高密度胆固醇水平高于非肌少症组（P＜0.05），体质指数、体重、去脂体重、腰臀比、基础代谢、体脂百分比、肌肉质量、血红蛋白、淋巴细胞百分比、γ?谷氨酰转肽酶、尿酸、总胆固醇、三酰甘油、低密度胆固醇水平明显低于非肌少症组（P＜0.05）。Logistic回归分析结果显示，年龄的增长（OR=1.129, P＜0.05），高体脂百分比（OR=1.118, P＜0.05）增加老年住院患者肌少症发生风险，高BMI（OR=0.225, P＜0.05）、高尿酸（OR=0.994, P＜0.05）降低老年住院患者肌少症发生风险。结论 兰州老年住院患者肌少症检出率较高，高龄、高体脂百分比是肌少症发生的危险因素，高体质指数、高尿酸是肌少症发生的保护因素。 |
| 英文摘要: |
| Objective This study investigated risk factors for sarcopenia in elderly inpatients (60+) in Lanzhou using propensity score matching (PSM), aiming to strengthen the foundation for sarcopenia screening and prevention. Methods Elderly inpatients from the Second Ward of the Geriatric Department at the First Hospital of Lanzhou University were selected. Following sarcopenia screening, they were categorized based on comorbidities including hypertension, coronary heart disease, and diabetes. With 1:1 PSM, the subjects were divided into sarcopenia and non-sarcopenia groups. After matching, demographics, body composition, and biochemical parameters were analyzed. The sarcopenia risk factors were identified using multivariate logistic regression. Results Of the 743 patients, 183 were diagnosed with sarcopenia. The detection rate was 25.49%. Specific parameters, such as age and high-density lipoprotein, were higher in the sarcopenia group (P<0.05). While other factors like BMI and muscle volume were lower (P<0.05). Logistic regression showed increasing age and body fat percentage raised sarcopenia risk, while high BMI and uric acid reduced it. Conclusion Elderly inpatients in Lanzhou have a significant sarcopenia prevalence. Aging and increased body fat are risk factors, while high BMI and uric acid are protective against sarcopenia. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |