由“虚瘀”理论探讨耆鹿逐痹胶囊防治肾虚血瘀型骨质疏松的作用
The effect of QiluZhubi capsule on preventing and treating osteoporosis of kidney deficiency and blood stasis type was discussed
  
DOI:10.3969/j.issn.1006-7108.2024.06.018
中文关键词:  虚瘀理论  耆鹿逐痹胶囊  肾虚血瘀型  骨质疏松  中医中药
英文关键词:deficiency stasis theory  QiluZhubi capsule  Kidney deficiency and blood stasis type  osteoporosis  traditional Chinese medicine
基金项目:国家自然科学基金(82074183);浙江省自然科学基金(LZ22H270002);浙江省中医药科技计划中医药现代化专项基金(2020ZX009)
作者单位
蒋欣1 杨小龙1 张泽臣1 李威1 叶佰盛1 陈琪1 丰杰1 黄振1 黄海1 刘康2 史晓林2* 1.浙江中医药大学第二临床医学院浙江 杭州 310053 2.浙江中医药大学附属第二医院浙江 杭州 310005 
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中文摘要:
      骨质疏松症是一种以骨量下降为主要特点的骨代谢性疾病,归属中医“骨痿”范畴,其发病率正逐年上升。常兼见疼痛症状且易引发病理性骨折,让患者深受其折磨。“虚瘀”理论是历代医家所探讨的,有关骨痿的一个重要病机,其核心为肾虚为本,血瘀为标。该文由论述“虚瘀”理论引申至骨痿肾虚血瘀病因病机,进而探讨“补肾活血法”相关治则。同时指出耆鹿逐痹胶囊具有益气养阴,补肾健骨,活血祛风之功效,与“补肾活血法”相符,而且其组成药物所含的有效成分对骨质疏松症也有一定程度的防治作用,从而可以得出耆鹿逐痹胶囊可用于防治肾虚血瘀型骨质疏松症,为临床运用其防治骨质疏松症奠定了一定的基础。
英文摘要:
      Osteoporosis is a bone metabolic disease characterized by a decrease in bone mass, which belongs to the category of "bone flaccidity" in Chinese medicine, and its morbidity is rising with each passing year. It is often accompanied by painful symptoms and easy to cause pathological fractures, so that patients suffer from it. The theory of "deficiency of blood stasis" is an important pathogenesis of bone flaccidity discussed by doctors of all dynasties. Its core is kidney deficiency as the foundation and blood stasis as the standard. In this paper, the theory of "deficiency of blood stasis" is extended to the cause and pathogenesis of kidney deficiency and blood stasis of bone potence, and then the relevant treatment of "tonifying kidney and activating blood" is discussed. At the same time, it is pointed out that QiluZhubi capsule has the effect of invigorating qi and nourishing Yin, invigorating kidney and strengthening bones, promoting blood circulation and dispelling wind, which is consistent with the "invigorating kidney and invigorating blood circulation method", and the active ingredients contained in its components also have a certain degree of prevention and treatment on osteoporosis, so it can be concluded that QiluZhubi capsule can be used to prevent and cure osteoporosis of kidney deficiency and blood stasis type. It has laid a certain foundation for clinical application of osteoporosis prevention and treatment.
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