2型糖尿病与骨质疏松症药物治疗间相关性研究进展
Research progress on the drug therapy correlation between type 2 diabetes and osteoporosis
  
DOI:10.3969/j.issn.1006-7108.2024.06.024
中文关键词:  2型糖尿病  骨质疏松症  药物治疗  骨代谢
英文关键词:type 2 diabetes  osteoporosis  drug therapy  bone metabolism
基金项目:陕西省科技厅项目(2019SF-282);西安市科技局项目[20YXYJ0012(4)]
作者单位
孙晴1* 王世尧2 祝志强1 王墉琦1 李佳1 李汉1 赵宇2 1.西安市中医医院陕西 西安 710021 2.陕西中医药大学陕西 咸阳 712046 
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中文摘要:
      2型糖尿病是目前世界上最为常见的慢性疾病之一,这些患者并发骨质疏松症的概率远高于非糖尿病患者。另外,糖尿病合并骨质疏松症出现的致残率与死亡率极高,严重影响人类生活健康。不少研究发现2型糖尿病与骨质疏松症有许多共同的高危发病因素以及发病机制,但二者药物治疗之间的相关性仍存在较大争议,未能给予临床用药准确的参考价值。因此,笔者通过归纳分析总结近些年最新参考文献,发现两者在药物治疗方面的关联性十分密切,如某些抗2型糖尿病药物不仅可以改善血糖水平而且还能调节骨平衡,某些抗骨质疏松症药物对降低血糖又具有一定的价值,不过两者药物治疗之间的关联性还需要更进一步的研究探索。因此,笔者探讨了2型糖尿病与骨质疏松症两者药物治疗之间的相关性并作一综述,以期能够为临床治疗提供一些参考价值。
英文摘要:
      Type 2 diabetes is one of the most common chronic diseases in the world. The probability of osteoporosis in these patients is much higher than that in non diabetes patients. In addition, the morbidity and mortality rate of diabetes combined with osteoporosis is extremely high, which seriously affects human life and health. Many studies have found that type 2 diabetes and osteoporosis have many common high risk factors and pathogenesis, but the correlation between their drug treatment is still controversial, which fails to give accurate reference value to clinical medication. Therefore, the author summarized the latest references in recent years through induction and analysis, and found that the relationship between the two drugs in drug treatment is very close. For example, some anti type 2 diabetes drugs can not only improve blood sugar level but also regulate bone balance, and some anti osteoporosis drugs have certain value in reducing blood sugar, but the relationship between the two drug treatment needs further research and exploration. Here, the author discusses the correlation between the drug treatment of type 2 diabetes and osteoporosis, and makes a review, hoping to provide some reference value for clinical treatment.
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